| Background:Dysmenorrhoea is the most common disease in gynecology.Women may have different degrees of abdominal pain from menarche to menopause,which may cause inconvenience to life.It will also cause a great deal of psychological,physical and psychological harm to women.It will bring tremendous physiological and psychological pressure to patients,affect the quality of life of patients,reduce work and learning efficiency,and cause patients to fear menstrual cramps.In recent years,as the burden of work,study,and life has increased,the incidence of dysmenorrhea has continued to increase.Therefore,early treatment of dysmenorrhea is particularly important to protect women’s health.We are also constantly seeking the best treatment solutions.Useful medical results.The primary dysmenorrhea,in addition to the common cold coagulation,dampness and hot Accumulation and other syndromes,the use of the appropriate treatment by the method of warm blood circulation,dampness and heat,etc,improved,but there are still some patients with pure heat and warming effect is not good,clinical often overlooked,these patients are often cold and hot mixed,the body appeared hot and cold symptoms,its pathogenesis is complex,after more continuous clinical observation and summary,mostly due to liver and kidney yang deficiency caused by the heat Cold evidence.Therefore,this study selected liver-kidney yang deficiency type,primary dysmenorrhea with upper fever and cold symptoms as a clinical research object,to investigate the clinical efficacy of Wumei pill addition and subtraction,and compared with the oral contraceptive drug Marvelon,as Wumei Pill.Addition and subtraction treatment of liver and kidney yang deficiency in the cold syndrome on the primary dysmenorrhea provide theoretical basis.Objective:By observing the plum pill and subtract the treatment group and control group in treatment of oral contraceptives,mom rich grand the clinical curative effect of the 30 patients with primary dysmenorrhea,explore the plum pill and subtract the clinical curative effect of treatment of liver and kidney Yang deficiency type of primary dysmenorrhea.Methods:According to the inclusion criteria and exclusion criteria,60 cases of primary dysmenorrhea were treated with liver-kidney yang deficiency-type syndrome and 60 cases were randomized.They were randomly divided into Wumei pill addition and treatment group and Mafulong control group.Each of 30 cases.The treatment group began to take it on the fifth day of menstruation.After serving for seven days,the patients were treated by adding or subtracting drugs according to clinical symptoms.The treatment was stopped after 3 months of regular treatment,and no other drugs were taken during the period of Chinese medicine.The control group oral contraceptives Marvelon on the fifth day of menstruation,1 time/day,1 tablet/time,taken at bedtime,oral for 21 consecutive days,continuous standard treatment for 3 menstrual cycles,the dysmenorrhea score as the assessment criteria,observation of dysmenorrhea Degree and scores of TCM symptoms change and efficacy.Results:There was no statistical difference between the treatment group and the control group in the disease course distribution,age distribution,dysmenorrhea symptom score,dysmenorrhea score,and individual TCM symptoms(p>0.05).The two groups were comparable.① The total effecti’ve rate of clinical efficacy in both groups was 90.00%in the treatment group and 83.33%in the control group.The treatment group was significantly better than the control group(P<0.05).②Comparison of dysmenorrhea scores after treatment between the two groups was 5.00±3.37 in the treatment group and 6.45±4.11 in the control group,and the treatment group was significantly better than the control group(P<0.05).③Comparison between the two groups of TCM syndromes,the treatment group was 90.00%,and the control group was 80.00%.The treatment group was significantly better than the control group(P<0.05).④Comparison of the efficacy of individual TCM symptoms,the total effective rate of the treatment group was significantly better than that of the control group,and the treatment group was significantly better than the control group(P<0.05).⑤ The TCM symptom scores of the two groups after treatment were 5.77±5.46 in the treatment group and 10,87±5.61 in the control group.The treatment group was significantly better than the control group.⑥The recurrence rate was 12.50%in the treatment group and 50.00%in the control group.Therefore,Wumei Pill has a good clinical effect in the treatment of primary dysmenorrhea of women with liver-kidney yang deficiency and upper heat and cold syndrome.Its clinical curative effect is better than that of Mafulong in the treatment of female primary dysmenorrhea.Conclusion:Wumei Pill has a good clinical effect on the treatment of primary dysmenorrhea of cold syndrome with liver-kidney yang deficiency,and it is obviously better than the control group in the degree of dysmenorrhea and symptoms of TCM.Therefore,it can solve the problem of dysmenorrhea in women and also reduce the clinical symptoms of patients.In terms of long-term efficacy,Wumei Pill treatment for primary dysmenorrhea in women is also worthy of medical promotion and application. |