Sex Difference Of Influencing Factors Of Mild Cognitive Impairment In Elderly From Lu'an City Of Anhui Province

Objectives: This study explored the sex differences in the prevalence of mild cognitive impairment(MCI)in elderly from Lu'an city,Anhui province.We analyzed gender differences of the influencing factors of mild cognitive impairment.Methods: Study subjects were identified from the health and environmental controllability of elderly cohort study in Lu'an city,Anhui province.Subjects aged over 60 years old were enrolled from two communities representing urban and rural areas in Lu'an city.All subjects completed face-to-face interviews and health physical examinations.The interviews included socio-demographic characteristics(age,sex,education,occupation,marriage)and lifestyles(working,smoking,drinking,etc.).Height,weight,handgrip,skinfold thicknesses(triceps,subscapular,abdominal),fasting blood glucose,and blood pressure were also examined.The subjects were assessed using the Mini-Mental State Examination to measure MCI and the Geriatric depression scale to measure emotional status.Multivariate logistic regression was conducted analyze the influencing factors of MCI.Results: Of the 1080 participants,1005 subjects with complete data were included in the analysis,including 453(45.1%)males and 552(54.9%)females.The prevalence of mild cognitive impairment was 11.6%(53/453)among elderly men and 18.8%(104/552)among elderly women.In univariate analyses,area,age,education,marriage,living alone,depression,exercise,sleeping time,household time,handgrip,BMI,and subscapular skinfold thicknesses(triceps,subscapular,abdominal)were significantly associated with MCI in males(P<0.05).At the same time,area,age,education,marriage,occupation,living alone,depression,exercise,sedentary time,household time,salt-addicted,oil-addicted,diet banlance,handgrip,BMI,and subscapular skinfold thicknesses(triceps,subscapular,abdominal)were significantly associated with MCI in females(P<0.05).Multiple factor analysis showed that handgrip and household time were influencing factors in males(P<0.05),while age,depression,BMI,and subscapular skinfold thicknesses were influencing factors in females(P<0.05).Conclusions: There were sex differences in the prevalence of MCI in elderly people in Lu'an city.The MCI of influencing factors were including handgrip strength and household time over 1 hour in elderly men.The MCI of influencing factors were age over 70 years,mild to severe depression,underweigh and higher subscapular skinfold thicknessest in elderly women.