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The Clinical Features Of 84 Cerebral Palsy Children With Epilepsy

Posted on:2019-06-20Degree:MasterType:Thesis
Country:ChinaCandidate:X ZhangFull Text:PDF
GTID:2394330545461346Subject:Academy of Pediatrics
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ObjectiveTo study the features of type epileptic seizures,brain imaging and electroencephalogram(EEG)of epilepsy(EP)in children with cerebral palsy(CP).MethodsThe linical data of 84 children with CP and EP were collected from January 2014 to December 2016 in the First Affiliated Hospital of Ahhui Medical University.Meanwhile,57 cases of children with CP without EP were selected as control group to explore clinical characteristics of EP in children with CP.Statistical processing by using SPSS17.0 statistical software.ResultsThe two groups were statistically significant in spastic tetraplegia,spastic hemiplegia and spastic diplegia(P<0.05).The proportion of spastic tetraplegia(47.6%)and spastic hemiplegia(25%)in the group of CP with EP was significantly higher than that in control group(19.3% and 8.8%),while the proportion of spastic diplegia(52.6%)in the control group was significantly higher than that of CP with EP group(16.7%).45 cases which accounts for 53.6% have the onset of EP before one years old.Among them,spastic tetraplegia(45%)were dominant.Among CP children complicated with EP,39cases(46.4%)were tonic-clonic seizures,18 cases(21.4%)were of focal seizures,13cases(15.5%)were infantile spasms.There were 5 cases(6%)of tonic seizures and myoclonic seizures,2 cases of clonic seizures(2.4%),1 case of absence seizure and atonic seizures(1.2%).Compared with control group,the abnormal changes of brain imaging and EEG in the CP with EP group were statistically significant(P<0.05).The proportion of gray matter or gray and white matter damage,infection and dysplasia in CP with EP group(32.1%)was significantly higher than that in the control group(8.8%),while the proportion of white matter injury in the control group(36.8%)was higher than that in CP with EP group(11.9%).The proportion of localized epileptic discharges in the EEG of in CP with EP group(50%)was significantly higher than that of the control group(15.8%).ConclusionEP is more likely to occur in children with spastic tetraplegia.Most onset time of EP is before one years old,and tonic-clonic seizures is dominate in CP children.The brain imaging and EEG are of great significance to early diagnosis of EP and the judgement of the prognosis.
Keywords/Search Tags:Cerebral palsy, Epilepsy, Children, Clinical features
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