Design And Optimization On Measurement And Control System Of Automatic Biochemical Analyzer

Biochemical detection is an important part of clinical medicine tests.With the development of medical science and the improvement of medical conditions in our country,people put forward higher requirements for the detection of biochemical indicators.As the main tool of biochemical analysis,biochemical analyzer has received more and more attention.At present domestic biochemical analyzers are far behind the foreign products in terms of accuracy,speed and stability.Thus the domestic products are less competitive than foreign ones in the market.However,imported equipment exists many problems such as closed detection systems and expensive reagents.Therefore,it is urgent to develop a high-performance automatic biochemical analyzer with independent intellectual property rights.Based on the above background,this project designed a small desktop automatic biochemical analyzer measurement and control system,which can automatically measuring the weak light signal of the microplate.Meanwhile,the measurement and control system of this biochemical analyzer is optimized in terms of the drawbacks such as large noise,single detection method etc.This optimization of biochemical analyzer improves its performance and provides a foundation for the follow-up indoctrination.This work mainly includes two parts:(1)The designed biochemical analyzer consists of the hardware platform,software of host and slave computers.The hardware is designed via modular structure method.It includes controller module,power module,calibration module,detection module,motor and the drive module,serial communication module and so on.The slave computer software uses C language as the development tool to complete the initialization of the hardware system,the calibration of the motor,the communication with the host computer.Then,it executes the commands from the host computer to complete the biochemical detection through driving the motor movement.The host computer software uses the Visual Basic language as a development platform and adopts a structured programming mode to implement the PC control of the entire measurement and control system.The main functions of the host computer software include serial port automatic identification and serial port communication,detection mode selection,information entry,back-end path planning,access database storage,data processing,curve generation,medical history printing,and information searching.(2)The theoretical optimization of the measurement and control system of automatic biochemical analyzer:The theoretical optimization of the biochemical analyzer includes the optimization of running accuracy and the optimization of detecting speed.First,this study proposes a new s-curve algorithm to replace the traditional trapezoidal curve algorithm in the process of motor drive.This is aimed to achieve the precise control of the transmission process of biochemical analyzer.This new s-curve algorithm realizes the flexible start and stop of the drive motor,the decreased operating noise,and improved running accuracy.Second,there are many drawbacks in matrix microplate detection of medium and small biochemical analyzer,such as too many detecting sites,single route and difficult path planning.To overcome this drawback,a path planning algorithm based on the dynamic planning method is put forward in this work.This novel algorithm transforms the multi-stage decision-making process several one-stage optimization process and then solves the optimal path.The application of this method greatly decreases the single-cycle detection time of the instrument and improves the detection speed.