The Design And Study Of Computing Model And Nanostructures Based On DNA Self-Assembly

Molecular self-assembly is process, in which some molecular of a system gather into regular structure, according to certain rules without the action of external force. DNA is the carrier of genetic information, having inherent features of typical nanometer scale,stable and flexible structure, robust encoding, strong operability and powerful for Data-Parallel. Because of these properties, the application of self-assembly based on DNA has been widely developed in the fields of biosensing, molecular computing, nanostructrue and so on.This paper mainly focuses on the application of molecular computing and nanotechnology based on DNA self-assembly. Firstly, it introduces the backgroud and status of DNA computing and DNA nanotechnology, then summarizing the basics of DNA computing. Secondly, it elaborates a novel single-stranded DNA tile and constructes DNA XOR logic gate, DNA accumulator, DNA summator, DNA subtractor and so on by means of model design, simulation and experiment. Thirdly, under the foundation of existing hierarchical DNA sub-tiles, we construct two-dimensional lattices and three-dimensional nanotubes via designing the sequence, and then we analyze the feasibility of constructing two-dimensional lattices and three-dimensional nanotubes based on DNA sub-tiles, and discuss the impacts of difform DNA tiles on mesh construction, size and yield of the tubes.Finally, this paper makes a brief summary of research tool, the design process of the model and the algorithm and the simulation and experimental results. And then we discuss the impacts of the construction of DNA tiles on experimental result and improvement project, and then point out the prospects of future studies.