| Objective:1.To investigate the epidemiological characteristics of mycoplasma pneumoniae(MP)infection in children in Ningbo;2.To explore the correlation between MP infection,climate and air pollution factor PM2.5.Methods:With application of the passive agglutination method,MP-IgM(Immunoglobulin M)was detected in children who were hospitalized in Ningbo Women and Children' Hospital from 2013 to 2015.At the same time,the meteorological data(including monthly mean temperature,monthly mean relative humidity,monthly mean wind speed,monthly total precipitation and monthly total sunshine)and the monthly average data of air pollution factor PM2.5 in Ningbo from 2013 to 2015 were collected.The positive rate of different year,season,gender and age groups was compared by using chi square test.And the correlation between MP infection rate,climate factors and air pollution factor PM2.5 was analyzed by using the Pearson correlation analysis and stepwise regression analysis approach.Results:1.Altogether 28861 cases were detected in the 3 years from 2013 to 2015,among which 6618 cases were infected with MP and the total detection rate accounted for 22.93%;the MP infection rate in the year 2013,2014 and 2015 was 20.95%(2511/11986),21.73%(1244/5725)and 25.68%(2863/11150),indicating that the detection rate was increasing year by year.Among all the MP infection cases,the male detection rate was 20.51%(3534/17232),lower than female detection rate(26.52%,3084/11629).2.The detection rate of MP in the various age groups was listed as follows: 4.66% in Baby Group,23.79% in Infant Group,33.11% in Pre-School Group and 34.81% in School-Age Group.The detection rate was increased with age,which was the highest in School-Age Group and the lowest in Infant group.3.According to the seasonal distribution analysis of 28861 cases detected from 2013 to 2015,the detection rate in spring was 20.18%(1453/7201),in summer was 26.94%(1977/7339),in autumn was 25.70%(1843/7170)and in winter was 18.81%(1345/7151).The detection rate was the highest in summer and lowest in winter.4.According to the correlation and regression analysis between the MP infection rate and climate factors,it was shown that: the MP infection rate was moderately positively correlated with the monthly average temperature,low positively correlated with the monthly average humidity and monthly total precipitation,but uncorrelated with the monthly average wind speed and the monthly total sunshine.The regression equation between MP infection and monthly average temperature was MP infection rate(%)=15.437+0.414 × monthly average temperature(?),which indicated that the MP infection rate increased with the increase of monthly average temperature.5.According to the correlation and regression analysis between the MP infection rate and air pollution factor PM2.5,it was shown that: the MP infection rate was moderately negatively correlated with monthly average PM2.5.The regression equation between MP infection rate(%)and the monthly average PM2.5 was obtained: MP infection rate(%)= 29.777-0.162×PM2.5(?g /m3),namely,PM2.5 decreased each 1?g /m3,the MP infection rate would increase by 0.16%.Conclusion:1.The MP infection rate of children in Ningbo shows a year-by-year increasing trend in 2013-2015.2.The female MP infection rate is higher than male;the MP infection rate increases with age and is commonly occurred in school-age children;and it is the highest in summer,the lowest in winter.3.The climate factors have an impact on the MP detection rate.MP detection rate is positively correlated with monthly average temperature,monthly average relative humidity and monthly total precipitation;and it increases with the increase of temperature.4.The MP detection rate increases with the decrease of PM2.5.MP infection rate(%)= 29.777-0.162×PM2.5(?g/m3). |
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