| Objective: Observe the clinical curative effect of BuYangAnKun Fang combined with Moxibustion Shenque Acupoint,which is applied to treat premature ovrarian failure,kidney deficiency type,and to further explore the related mechanism,looking for more ways for clinical treatment.Methods: We totally observed 60 patients of POF(kidney deficiency type)and it was divided into two groups randomly.The treatment group takes BuYangAnKun Fang combined with Moxibustion Shenque Acupoint,while the control group takes Jiarong capsule,treatment for 3 months,which are compared to observe their clinical symptom scores,TCM syndrome integral,clinical efficacy and impacts on FSH,LH,E2,monitoring endometrial thickness changes.After the research,carring out a statistical analysis on the differences between the treatment group and control group.Results:The total curative effect in treatment group was 83.33%,46.67% in the control group,there was significant difference(P<0.05).The syndrome curative effect of traditional Chinese medicine in treatment group was 83.33%,63.33% in thecontrol group,there was significant difference(P<0.05).The FSH level and the LH level of the two groups are both obviously decreased after treating,which has significant differences compared with its original level(P<0.01)and the control group(P<0.01).The E2 level is increased of the two groups after treating,which has significant differences compared with ex-treatment(P<0.01)and the control group(P<0.01).After treatment,the comparison of within two groups and between groups,the endometrial thickness has significant differences(P<0.01).Conclusion: BuYangAnKun Fang combined with Moxibustion Shenque Acupoin has remarkable effect in treating kidney deficiency type premature ovrarian failure.The mechanism may be through improving the function of hypothalamic-pituitary-ovarian axis,make the body enhanced reactivity,adjust the sex hormone levels in the body,significantly improve patients' symptoms. |
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