Epidemiological Characteristics Of Thyroid Dysfunction In Urban And Rural Residents Of Jilin Province

Objectives:To investigate the prevalence and risk factors of thyroid dysfunction in urban and rural areas in Jilin province by conducting epidemiological investigation among urban and rural residents Jilin province Methods:The stratified cluster random sampling method was performed to select urban and rural permanent residents over 18 years in Jilin province and then a cross-sectional survey was conducted.Finally,2232 residents were included in the study,including 1148 urban residents,accounting for 51.4%,and 1084 rural residents,accounting for 48.6%.The participants completed questionnaire,physical examination,laboratory biochemical tests.The original data were input through Epidata software by two different person,the third person was responsible for checking,exporting data.The final data were analyzed by SPSS 18.0 software.Results:1,The participants were divided into urban and rural group,in urban group,the prevalence rate of hyperthyroidism,subclinical hyperthyroidism,hypothyroidism,subclinical hypothyroidism were 0.78%,0.78%,1.30%,10.62%,respectively,and the standardized prevalence rate were 0.72%,0.77%,1.58%,10.52%,respectively;In rural group,the prevalance were 1.01%,0.37%,2.21%,9.59%,respectively,and the standardized prevalence rate were 0.95%,0.34%,1.99%,9.53%,respectively,.The prevalence of these four kinds of thyroid dysfunction has no statistically significant difference between urban and rural areas.2,To conduct single factor analysis of prevalence on urban and rural hypothyroidism,subclinical hypothyroidism,in urban group,prevalence of hypothyroidism in females was higher than that in males,the prevalence of hypothyroidism is different between different age groups,the prevalence of subclinical hypothyroidism is different between different urinary iodine level and different smoking quantity,the difference was statistically significant(P<0.05);in rural group,prevalence of hypothyroidism and subclinical hypothyroidismin females was higher than that in males,the prevalence of subclinical hypothyroidism is different between different smoking population,the difference was statistically significant(P<0.05).3,To analysis the influencing factors of hypothyroidism and subclinical hypothyroidism in urban and rural areas,in the urban group,female and age are risk factors for the prevalence of hypothyroidism,the urinary iodine concentrations over 300 ?g/L is a risk factor for the prevalence of subclinical hypothyroidism;in rural group,only female is a risk factor for the prevalence of subclinical hypothyroidism.4,Whether preschool children or adults,the urinary iodine level of urban group were significantly higher than that of the rural group(P < 0.01),at the same time,the study also found that urinary iodine levels of urban population with subclinical hypothyroidism is higher than that of normal thyroid function(P<0.05);In rural group,urinary iodine levels in patients with subclinical hyperthyroidism group is higher than that of normal thyroid function(P< 0.05).Conclusions:1,The overall prevalence rates of hyperthyroidism,subclinical hyperthyroidism,hypothyroidism and subclinical hypothyroidism in urban and rural residents were not statistically different.The prevalence rates of subclinical hypothyroidism in urban and rural areas were higher in the four kinds of thyroid dysfunction.2,The female,older ega are risks factor of hypothyroidism for urban residents,Iodine excess(the urine iodine level over 300 ?g/L)is a risk factor of subclinical hypothyroidism for urban residents,The female is a risk factor of subclinical hypothyroidism for rural residents.3,Iodine nutritional status is adequate in city residents and sufficient in rural residents,there is a relationship between high iodine and subclinical hypothyroidism,subclinical hyperthyroidism.