Research On The Relationship Between The Miscellaneous Characteristics Of Perimenopause Obesity Phlegm Syndrome And Body Fat Distribution

Purpose:Study the differences of syndrome elements characteristic and body fat distribution between the patients with perimenopause obesity phlegm syndrome and the patients with child-bearing period obesity phlegm syndrome;besides,discuss the correlation between the syndrome elements characteristics of the patients with perimenopause obesity phlegm syndrome the clinical obesity measurement,blood fat.Finally,some references on TCM differentiation are provided for clinical diagnosis and therapy of the patients with perimenopause obesity phlegm syndrome.Methods:Syndrome factor differentiation is used to analyze the syndrome elements characteristic of 127 patients with perimenopause obesity phlegm syndrome and 104 patients with child-bearing period obesity phlegm syndrome.Simple body fat parameters and CT accurate measurement of body fat parameters are adopted to analyzed body fat distribution of female patients with obesity phlegm syndrome.Then,differences of syndrome factor and body fat distribution are analyzed about patients with perimenopause obesity phlegm syndrome and the patients with child-bearing period obesity phlegm syndrome from the perspective of phlegm syndrome.Finally,the correlation between syndrome factor of patients with perimenopause obesity phlegm syndrome and body fat parameters as well as blood fat is discussed.Results:1.The syndrome elements characteristics of the patients with perimenopause obesity phlegm syndrome:main disease is given priority to with liver,then followed by kidney,spleen,stomach,heart,lung and gallbladder;syndrome factors of the main solid and miscellaneous disease are dampness,heat,qi stagnation and blood stasis;syndrome factors of the main virtual and miscellaneous disease are yin deficiency,qi deficiency,yang deficiency and blood deficiency.2.The comparison of syndrome elements characteristics between the patients with perimenopause obesity phlegm syndrome and the patients with child-bearing period obesity phlegm syndrome:among syndrome factors of the disease location,compared with the patients with child-bearing period obesity phlegm syndrome,renal syndrome factor frequency of the patients with perimenopause obesity phlegm syndrome is high(P<0.01),the score of liver and kidney syndrome is higher than that of child-bearing period obesity phlegm syndrome(P<0.05,P<0.01).Spleen syndrome factor frequency of the patients with child-bearing period obesity phlegm syndrome is higher than the patients with perimenopause obesity phlegm syndrom(P<0.05).In the miscellaneous disease syndrome factors,compared with the patients with child-bearing period obesity phlegm syndrome,yin deficiency syndrome factor frequency of the patients with perimenopause obesity phlegm syndrome is higher(P<0.05);qi stagnation integral syndrome element of the patients with perimenopause obesity phlegm syndrome is also higher(P<0.05).3.The comparison of anthropometric parameters between the patients with perimenopause obesity phlegm syndrome and the patients with child-bearing period obesity phlegm syndrome:in the simple anthropometric parameters,the patients with perimenopause obesity phlegm syndrome has higher index in WHR(P<0.05);Similarly,in the anthropometric parameters of CT measurement,the patients with perimenopause obesity phlegm syndrome also has higher VFA(P<0.05).4.The relationship between syndrome elements of the patients with perimenopause obesity phlegm syndrome and their body mass index:in the simple anthropometric parameters,the integral syndrome element of the spleen has positive correlation with WC,WHtR and WHR(P<0.01).Phlegm syndrome element is positively correlated with WC,WHtR and WHR(P<0.05,P<0.01).The dampness syndrome element integral is positively correlated with WHtR and WHR(P<0.05).The integral of yin deficiency syndrome element is positively correlated with WC and WHtR(P<0.05).In the anthropometric parameters of CT measurement,syndrome elements have no obvious correlation with visceral fat area.5.The relationship between syndrome elements of patients with perimenopausal syndrome of phlegm and their blood lipid:the integral of phlegm syndrome element is positively correlated with serum total cholesterol(P<0.05);the integral of heat syndrome element is remarkable positively correlated with the Triglyceride(P<0.01);qi deficiency syndrome score is positively correlated with triglyceride(P<0.05).Conclusion:1.The disease location of the patients with perimenopause obesity phlegm syndrome has mainly relationship with liver,kidney and spleen.The nature of disease is intermingled deficiency and excess.Syndrome factors of the solid and miscellaneous disease are mainly dampness,heat,qi stagnation and blood stasis;syndrome factors of the virtual and miscellaneous disease are mainly yin deficiency,qi deficiency,yang deficiency and blood deficiency.2.For the patients with perimenopause obesity phlegm syndrome,the body fat distribution has close relationship with spleen,phlegm,dampness and yin deficiency syndrome of;the syndrome factor of phlegm,heat and qi deficiency has close relationship with the rising of blood lipid.3.The patients with perimenopause obesity phlegm syndrome are easier to lead to the pathological change of iver depression and qi stagnation,kidney yin deficiency.This phenomenon is fat redistribution of females in perimenopausal period.It is one of the pathological mechanisms about central obesity with visceral fat accumulation.