Clinical Observation Of Dampness Type Of Knee Osteoarthritis Treated By Duhuo Jisheng Decoction

Objective:To compare the clinical efficacy of this subject are the treatment of wind cold dampness type of knee osteoarthritis through clinical observation of Duhuojisheng Decoction and glucosamine sulfate of two drugs,mechanism and clinical research of Duhuojisheng Decoction the application value for clinical treatment of wind cold dampness type of knee osteoarthritis treatment improved better,provided a reliable theoretical basis for Duhuojisheng Decoction in clinical use.Methods:This study included patients were outpatients in Anhui orthopedics hospital of traditional Chinese medicine,during the period from September 2015 to September2016.A randomized,self controlled,parallel control and block experiment design method,choose the standard and get the complete follow-up of anemofrigid damp arthralgia of knee osteoarthritis in 60 cases,among them,25 cases were male,35 females,age range 45 ~ 75 years old,the average(62.6 + 8.56)years old.SPSS 19 was used to 60 cases of patients were randomly divided into two groups in accordance with the research,30 cases in each group: Duhuojisheng Decoction group(hereinafter referred to as the treatment group)and glucosamine sulfate group(hereinafter referred to as the control group).The gender,age,duration of disease,the score before treatment were statistically analyzed,excluding differences.The treatment group was treated with the combination of oral and functional exercise,one day a dose of water decoction,sooner or later.A course of treatment for two weeks,treatment of two courses.The control group was treated with oral glucosamine sulfate group with functional exercise,2 times a day,three times a day.A course of treatment for two weeks,treatment of two courses.Observe and record the details of the research subjects of the two groups score before treatment,the first treatment,second patients with knee joint: the treatment VAS score,Lysholm score,WOMAC Osteoarthritis Index scores before and after treatment in patients with liver and kidney function.Using statistical software SPSS 19 to 60 subjects from clinical trials group data were statistically processed and analyzed,compared before and after treatment in two groups of subjects were all observed indicators,to evaluate the clinical efficacy of two groups of drugs.Results:1 This topic before treatment for the two groups of subjects included gender,age,educational level,duration of disease,lesion site and X-ray imaging classification through statistical analysis,P > 0.05,with comparable clinical research.2 Before and after treatment VAS score: two groups before treatment VAS score were statistically analyzed,P > 0.05,the difference was not statistically significant;the treatment of the first course,second courses of treatment group and control group group VAS score and VAS score before and after treatment by statistical analysis(t test)were statistically significant(P < 0.05)that,two groups of drugs on the therapeutic effect of KOA were,but efficacy was significantly better than the control group in the treatment group.3 The two groups before and after treatment of knee joint Lysholm score: before treatment,the Lysholm scores of the two groups were statistically analyzed,P >0.05,the difference was not statistically significant;the treatment of the first course,second courses of treatment group and control group before and after each treatment score and scores were compared by statistical analysis(t test)were statistically significant(P < 0.05),two groups of drugs on the treatment effect of KOA were but the efficacy of the treatment group was significantly better than the control group.4 The two groups before and after treatment WOMAC Osteoarthritis Index score:two groups before treatment Osteoarthritis Index scores were statistically analyzed,P > 0.05,the difference was not statistically significant;the first course,second courses of treatment group and control group Osteoarthritis Index scores before and after each treatment of osteoarthritis index score comparison treatment the statistical analysis(t test)were statistically significant(P < 0.05),indicating that the two groups of drugs on treatment effect were KOA,but the efficacy of the treatment group was significantly better than the control group.5 The two groups before and after treatment the clinical efficacy comparison: the treatment group patients,of which 6 were cured,19 markedly effective,3 effective,2 ineffective,the total efficiency of 93.3%;control group of patients,of which 3were cured,14 markedly effective,8 effective,5 ineffective,the total efficiency of83.3%;through statistical rank test analysis,Z=-2.168,P = 0.030<0.05,that there was a significant difference,the difference was statistically significant,the total efficiency of the treatment group was significantly higher than the control group.Conclusion:Duhuojisheng Decoction and glucosamine has good clinical efficacy in the treatment of wind cold dampness type KOA patient's symptoms and recovery of joint function.But the former clinical effect is more significant,can significantly improve the life of patients,reduce the pain of patients,improve the function of knee joint.After the follow-up observation,the patients were satisfied with the curative effect and the recurrence rate was low.So this is an effective prescription for clinical treatment of wind cold dampness type KOA,this method is economical and practical,safe and effective,has good clinical value,is worthy of clinical application.