Clinical Observation Of Traditional Chinese Hinese Medicine And Acupuncture Combined With Mifepristone And Misoprostol In The Treatment Of Qi And Blood Deficiency Type Of Missed Abortion

Objective: To study the traditional Chinese medicine + acupuncture combined with mifepristone and misoprostol clinical curative effect of Qi and blood deficiency type of missed abortion,and acupuncture and moxibustion combined with the complete abortion rate,pregnancy sac discharge time,vaginal bleeding time and bleeding volume,curettage rate and serumβ-HCG,E₂,P value detection and other related laboratory indicators,to investigate the mechanism of action possibly,and offer theoretical basis for clinical treatment.Methods: The complete collection of 60 cases diagnosed as Qi and blood deficiency type of missed abortion,were randomly divided into treatment group and control group of 30 cases,the control group was treated with oral mifepristone combined with misoprostol;treatment group on the basis of drug abortion plus oral Decoction and fetal Yimu decoction,combined with acupuncture treatment.Observe the two groups of different times the number of cases of gestational sac discharge,vaginal bleeding time,bleeding volume,uterine curettage rate and the treatment of serum beta β-HCG,E₂,P changes.Results: 1.Comparison of clinical efficacy between the two groups after treatment After treatment,the total efficiency of two groups: the treatment group was 93.33%,83.33% in the control group,the two groups had no difference（p>0.05）;the two groups after treatment: the complete abortion rate was 63.33% in the treatment group and the control group was 30%,two groups had difference（p<0.01）.2.After the treatment of the two groups of gestational sac discharge time comparison The treatment group at different time: the number of cases of gestational sac discharge less than 6h in 9 cases;20 cases of less than 12h;less than 24 h in 25 cases;28 cases of less than 48h;the control group: less than 6h in 2 cases;7 cases of less than 12h;less than 24 h in 13 cases;25 cases of less than 48 h.There was a significant difference between the two groups in the number of cases of gestational sac discharge（p<0.01）.3.Comparison of vaginal bleeding time between the two groups The treatment group of vaginal bleeding time were less than 7d: 1 cases;13 cases of less than 10d;less than 14 d in 20 cases,8 cases;14d;control group: less than 7d in 0 cases;3 cases of less than 10d;less than 14 d in 10 cases,14 d 15 cases.There was significant difference between the two groups in vaginal bleeding time（p<0.01）.4.Comparison of vaginal bleeding after treatment in the two groups The treatment group of vaginal bleeding cases: less than 50 ml in 7 cases;50≤m L<100 for 13 cases;100<m L≤150 for 7 cases;>150m L 1 case;control group: less than 50 ml in 1 cases;50≤m L<100 for 7 cases;100<m L≤150 for 13 cases;>150m L 1 case.There was a difference in the amount of vaginal bleeding between the two groups（p<0.01）.5.of the two groups after treatment compared with the rate of curettage After treatment,the total effective 28 cases,in 2 cases,the rate was 7.14%;the control group after treatment the total effective 25 cases,in 7 cases,the rate was 31.81%.The two groups had statistical significance of the rate difference（p<0.01）.6.Comparison of the two groups after treatment.Serum beta β-HCG、P、E₂ value The two groups after treatment.Serum betaβ-HCG、P serum E₂ values were decreased,compared with that before treatment,there are differences（p<0.01）;but the treatment group.β-HCG、P serum E₂ value decreased significantly,there were significant differences between groups（p<0.01）.Conclusion: The self-made fetal Yimu Decoction plus acupuncture combined with mifepristone and misoprostol for treating qi and blood deficiency type of missed abortion,achieved a satisfactory therapeutic effect in clinic.It can improve the rate of complete abortion,promote the discharge of gestational sac,shorten the time of vaginal bleeding,reduce the amount of vaginal bleeding,reduce the incidence of uterine curettage,can significantly reduce the serum levels of HCG,P,E₂,Its mechanism may be related to traditional Chinese medicine,acupuncture and moxibustion to further promote the necrosis of the gestational sac,promote the release of necrotic tissue in pregnancy.