Regulation Of Expression Of The Bacterial Biofilm And Biyuanshu Oral Liquid For Chronic Rhinosinusitis Secretory Immunoglobulin A On People

Objective:Normal people and the depressed gall bladder with phlegm heat Biyuan ostiomeatal complex mucosa without bacterial biofilm formation were observed and Biyuanshu Oral Liquid on secretion of chronic rhinosinusitis ostiomeatal complex secretion type immunoglobulin protein A (slgA) Regulation, reveal the pharmacological mechanism of Qingdan discharge heat method for relying on the therapeutic effect of Nasosinusitis Relieving Oral Liquid to improve the body's immune function, prevent the occurrence of the disease, nasal five degrees of differentiation theory provide theoretical support.Methods:All subjects of this study were collected from patients in the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine and college students from Chengdu University of Traditional Chinese Medicine, a total of 20 cases of CRS group,10 cases of normal control group. To meet the inclusion criteria of patients with chronic rhinosinusitis treated by Biyuanshu oral liquid treatment, treatment for 2 weeks.The normal and CRS patients of ostiomeatal complex mucosal bacterial biofilm using scanning electron microscope,ELISA method was used to detect the CRS before and after the treatment of ostiomeatal complex secretion of immunoglobulin A (SlgA) content changes,and before and after the treatment of ostiomeatal complex secretion type immunoglobulin a numerical statistical analysis and exploration of Biyuanshu oral liquid and the relationship between immunoglobulin A secreting.Results:1. The depressed gall bladder with phlegm heat nasosinusitis patients 10 cases of ostiomeatal complex mucosa in 6 cases and biofilm formation and normal people in 10 cases,1 cases of the formation of bacterial biofilm.2. Normal people and the depressed gall bladder with phlegm heat Biyuan ostiomeatal complex secretion secretion type immunoglobulin A (slgA) content had significant difference.3. Before and after the treatment in the secretion of the depressed gall bladder with phlegm heat Biyuan ostiomeatal complex secretory immunoglobulin A (slgA) content had significant difference.Conclusion:Chronic sinusitis patients are more likely to form bacterial biofilm, the presence of bacterial biofilm may be one of the important causes of chronic nasal sinusitis; Normal people and chronic rhinosinusitis ostiomeatal complex secretion in human secretory type immunoglobulin protein A (slgA) treatment has significant difference, the people before and after treatment in patients with chronic rhinosinusitis secretion type immunoglobulin A (slgA) content had significant difference, suggesting that the level of SlgA content may be related to the pathogenesis of chronic rhinosinusitis, Biyuanshu oral liquid can improve sinusitis in patients with human secretory immunoglobulin A content, improve human immunity, reduce the occurrence of paranasal sinus disease.