Study Relativity Between Plasma CRP?LDL-C?HCY Of CHD Patient And Different TCM Syndromes

Objective:Study relationship between plasma CRP?LDL-C?HCY of CHD patient and different TCM Syndromes thus to explore some objective index for standardization of syndrome type of Coronary Heart Disease (CHD),and it could supply objective clinical date for Traditional Chinese Medicine(TCM) diagnosis and treatment of CHD patient.Methods:Collecting 112 patients with coronary heart disease in Affiliated Hospital Chengdu University of Traditional Chinese Medicine from June 2014 to March 2016. Carefully recording the clinical symptoms, tongue picture, pulse condition of these patients with coronary heart disease, and making syndrome differentiation of traditional Chinese medicine for them. Selecting the phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis, qi stagnation and blood stasis syndrome, qi and Yin deficiency syndrome as the study group, in addition, selecting 30 healthy persons as control group. To detected the level of plasma CRP?LDL-C? HCY, analyzed the relationship between plasma CRP? LDL-C?HCY and coronary heart disease (CHD) and the phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis, qi stagnation and blood stasis syndrome, qi and Yin deficiency syndrome.Results:The TCM dialectical types of 112 patients with coronary heart disease were distributed as follow:41 patients with phlegm and blood stasis mutual resistance syndrome,25 patients with qi deficiency blood stasis,21 patients with qi stagnation and blood stasis syndrome,15 patients with qi and Yin deficiency syndrome,10 patients with other TCM Syndromes. Statistically analyzed the results of age and gender of every TCM Syndrome, there were no significant difference(P>0.05).The level of plasma CRP?LDL-C?HCY were statistically significant difference of CHD compared to those in the control group (P<0.05).The level of CRP were statistically significant difference of qi and Yin deficiency syndrome and phlegm and blood stasis mutual resistance syndrome compared to qi deficiency blood stasis and qi stagnation and blood stasis syndrome (P<0.05), the results of comparison of CRP level between the two qi and Yin deficiency syndrome and phlegm and blood stasis mutual resistance syndrome and other two kinds of syndromes of CHD shows that, there were no significant difference(P>0.05).The results of comparison of LDL-C level between patients with different syndrome of CHD shows that, the level of LDL-C were statistically significant difference of qi stagnation and blood stasis syndrome and phlegm and blood stasis mutual resistance syndrome compared to besides two syndrome (P<0.05), the results of comparison of CRP level between the two qi stagnation and blood stasis syndrome and phlegm and blood stasis mutual resistance syndrome and other two kinds of syndromes of CHD shows that, there were no statistical significance(P> 0.05).The difference has no statistical significance of the level of different syndrome of CHD(P>0.05).Qi deficiency blood stasis syndrome has positive relationship with CRP? LDL-C?HCY. Qi stagnation and blood stasis syndrome has positive relationship with LDL-C. Qi and Yin deficiency syndrome has positive relationship with CRP. Phlegm and blood stasis mutual resistance syndrome has positive relationship with CRP? LDL-C.Conclusion:The most syndrome is phlegm and blood stasis mutual resistance syndrome, according 112 patients with coronary heart disease. Followed by Qi deficiency blood stasis syndrome?Qi stagnation and blood stasis syndrome?Qi and Yin deficiency syndrome, other types of syndrome were rare.The level of plasma CRP?LDL-C?HCY of CHD were high compared to those in the control group, they could supply objective clinical date for diagnosis and treatment of CHD patient.The higher the level of CRP?LDL-C?HCY in patients with CHD,the more likely it is that the syndrome of qi deficiency blood stasis.The higher the level of LDL-C in patients with CHD,the more likely it is that the syndrome of qi stagnation and blood stasis.The higher the level of CRP in patients with CHD,the more likely it is that the syndrome of qi and Yin deficiency.The higher the level of CRP?LDL-C in patients with CHD.the more likely it is that the syndrome of phlegm and blood stasis mutual resistance.Blood CRP?LDL-C?HCY has a certain reference value for CHD patients with TCM syndrome differentiation, and it can be regarded as the objective reference for TCM syndrome differentiation of CHD.