Relativity Research On TCM Syndrome Types Of Coronary Heart Disease And Plasma Homocysteine Level

Objective:The aim of the study was to investigate the distribution of TCM syndrome types in coronary heart disease(CHD),and explore the relativity between symptoms and TCM syndrome types of CHD,and explore the relationships between homocysteine(Hcy),serum lipids,hemorheology and TCM syndrome types,providing relative foundation for TCM syndrome types of CHD.By using modern detect methods.quantify TCM syndrome types.discuss their severe degree in order to direct clinic therapy,It can make clinic treatment more reliable.Method:218 patients with CHD were divided into eight groups according to TCM syndrome types.We investigated the distribution of TCM syndrome types,and investigated the relativity between symptoms and TCM syndrome types.The level of Hcy,serum lipids,hemorheology were tested in order to explore the relationships between TCM syndrome types and these index.By statistics test,analyze the relativities between Hcy and serum lipids,hemorheology,and get the multiple regression equation.Results:1.The following 20 symptoms among symptoms variable of CHD had difference in TCM syndrome types:chest pain,stabbing pain,gripping,thoracic pain involving the back,pain with fixed place,wheeze,severe wheezing,short breath,expectoration,thin white phlegm,fat, fatigue and hypodynamia,dizziness,insomnia,sweating,disinclination to talk,lower limb edema,diuresis,oliguria,asthma must not lie(P＜0.05).2.The level of plasma Hcy in CHD patients were higher than the normol lever(P＜0.01),The level of plasma Hcy was different among TCM syndrome types(P＜0.05),The level of Hcy in phlegm blocking heart vessel symdrome and heart blood stasis symdrome were higher than that in qi and blood deficiency symdrome and qi-deficiency blood stasis symdrome,the level of plasma Hcy was not different between the phlegm blocking heart vessel symdrome and the heart blood stasis symdrome,it was not different between the qi and blood deficiency symdrome and the qi-deficiency blood stasis symdrome either(P＞0.05);The level of plasma Hcy was different among CHD groups(P＜0.05),the lever of plasma Hcy in unstable angina(UA) group and acute myocardial infarction (AMI) group were higher than that in stable angina(SA) group,there are not significant differentiation between UA group and AMI group(P＞0.05).3.the lever of serum lipids,hemorheology was not different among TCM syndrome types of CHD(P＞0.05).4.There were statistic relativity between Hcy and HDL,Hct(P＜0.05).5.The distribution of the TCM syndrome types of CHD were different between stable angina and unstable angina(P＜0.05).Conclusion:1.following symptoms among symptoms variable of CHD can be used to diagnose TCM syndrome types:chest pain,stabbing pain,gripping,thoracic pain involving the back,pain with fixed place,wheeze,severe wheezing,short breath,expectoration,thin white phlegm,fat,fatigue and hypodynamia,dizziness,insomnia,sweating,disinclination to talk, lower limb edema,diuresis,oliguria,asthma must not lie.2.The level of plasma Hcy in CHD patients were higher than the normol lever,The level of plasma Hcy in phlegm blocking heart vessel symdrome and heart blood stasis symdrome were higher than that in qi and blood deficiency symdrome and qi-deficiency blood stasis symdrome;the lever of plasma Hcy in UA group and AMI group were higher than that in SA group.3,the lever of serum lipids,hemorheology was not different among TCM syndrome types of CHD.4.Plasma Hcy had negative relativity with HDL,and it had positive relativity with Hct.5.The distribution of the phlegm blocking heart vessel syndrome and the heart blood stasis syndrome in UA group were higher than that in SA group.