Spleen And Kidney Invigorate The Drain Turbidity Method For The Treatment Of Chronic Kidney Disease 2-4 Period Of Clinical Observation

Objective: According to the USRDS data in 2011 show that the prevalence of chronic renal failure from 2005 to 2008 was 11.0%,and predict there may be 712290 people in the United States go into the end-stage renal disease in 2015~[1].In our country,the first option is the CKD4-5 patients has a considerable part of the period,this is because the disease prevalence rate was 10.8% in adults,but only 12.5% is differ with the great awareness ~[2],it appeared the phenomenon.Chronic kidney disease is irreversible disease,its pathogenesis and treatment is a complex process,western medicine treatment of unilateral are hard to improve the clinical curative effect,therefore,in the process of treatment the modern method combined with traditional Chinese medicine(TCM)method provides a new train of thought for the people.The CKD in TCM pathogenesis and treatment of each have different views,through modern research are also made a more definite curative effect.This study by applying the method of invigorating kidney invigorate the circulation of drain turbidity treatment the phase of 2-4 CKD and contend for the spleen and kidney deficiency and blood stasis of TCM turbidity block patients,by observing the changes of renal function and relevant clinical indicators,to evaluate the effect of this method for CKD.Methods: From the January in 2014 to the January in 2016 in our hospital nephrology outpatient clinic or hospital 2-4 period and TCM syndrome type of spleen and kidney deficiency and blood stasis cloud block type of 62 patients with CKD were randomly divided into two groups.Of which only gives the western medicine control group of 31 cases of foundation treatment,treatment group 29 cases except for foundation treatment,combined with spleen and kidney invigorate the drain turbidity method,include: Huang qi 30 g,Shan yao 20 g,Fu ling 30 g,Xu duan 15 g,Chuang qiong 15 g,Da huang 10 g,Dan shen 15 g,Shan yu rou 30 g,Liu yue xue 30 g,Hong hua 10 g,Ban xia 15 g,Dang gui 20 g.Water decoction,a dose of daily,morning and evening all take.Treatment for 3 months.Observe clinical symptom integral and Scr,BUN and blood to decide to decide microglobulin,urine with 2 microglobulin,Cyx C,blood 1 microglobulin,urine microglobulin changes before and after the treatment,compared ?to all sorts of change and using SPSS 22.0 according to different data types to take the corresponding statistical methods for analysis.Results:(1)The clinical curative effect: the spleen kidney invigorate the drain foundation treatment the total effective rate was 82.76%,turbidity method that simple foundation treatment the total effective rate was 51.62%,after comparing the former is superior to the latter(P<0.05);(2)The doctor of traditional Chinese medicine clinical symptoms integral,spleen and kidney invigorate the drain turbidity method combined western medicine foundation treatment group and western medicine treatment group can make effectively reduce the patient's clinical symptoms of traditional Chinese medicine integral,P<0.05,and before and after treatment the treatment group was more obvious(P<0.05);(3)Laboratory indexes,spleen and kidney invigorate the drain turbidity method foundation treatment group and simple foundation treatment group to a certain extent,reduce blood microglobulin,urine ?1 microglobulin,BUN,Scr,2 microglobulin decide Cyx C,blood,urine to decide 2 microglobulin,comparison before and after the treatment(P<0.05),and the treatment group is more apparent.Conclusion: For early metaphase CKD patients,spleen and kidney invigorate the drain turbidity method can to a certain extent,improve the clinical symptoms and some relevant laboratory index(Scr,BUN,blood to decide to decide microglobulin,urine with 2 microglobulin,Cyx C,blood microglobulin,urine ?1 microglobulin),prompt the spleen kidney invigorate the drain turbidity may middle for the treatment of patients with CKD have certain significance.