The Experimental Study On The Two Elements Of The Internal Organs In The Treatment Of Tung Spleen Deficiency Syndrome With Five Elements

Objective: From the point of view of traditional Chinese medicine of the organs as a whole, the use of the principle of five elements allelopathy, Chai Weiyi powder as basic combined with spleen, lung and liver wood between students gram relation to intervene in the lung and spleen deficiency model, and by Jiawei Yigong powder and Huang Weiyi power scattered group. Through the analysis of the index and data, to illustrate the use of soothing liver and invigorating spleen lung treatment of lung and spleen deficiency syndrome effect is better than the method of replenishing qi to invigorate spleen and spleen nourishing lung method, hope to provide new ideas for clinical treatment of lung and spleen deficiency, improve the clinical efficacy.Methods: young male Wistar rats were randomly divided into 5 groups, namely control group, model group, Yiqi Jianpi group, spleen nourishing group, Shugan Jianpi Yangfei group; the smoke plus papain atomizing compound factors copy "lung deficiency syndrome animal model, reserpine injection duplicate the" Spleen Deficiency "animal modeling, 30 days, thirty-first days randomly selected rats were observed in the lung, stomach, small intestine pathological changes. After model successfully entered the treatment period, started in accordance with the experimental design of intragastric administration of Shuganjianpi Yangfei group to Weiyi Chai Gong powder orally, volume measurement by 1ml/100 g conversion; spleen Raise Lung Group to be Weiyi Huang Gong powder orally, according to the 1ml/100 g conversion volume measurement; Yiqi Jianpi group received intragastric administration of jiaweiyigong powder, according to the 1ml/100 g conversion volume measurement; control group, model group were given saline, 1ml/100 g conversion volume according to the measurement of.14 days after the determination Index; observation of rats in each group, the overall situation; he staining were observed after lung, stomach, basic pathologic changes of small intestine; abdominal aortic blood was taken, after blood samples were centrifuged to get the serum D-xylose content determined by phloroglucinol method, ELISA Kit determined for motilin, gastrin content. Using SPSS19.0 software processing experimental data.Results: 1, Through the overall observation of the animal model and the lung, stomach, small intestine tissue pathological results confirmed that the "lung spleen two deficiency" model of animal reproduction is successful, so as to provide a basis for the successful experiment.2, The results of the experiment: Two serum D-xylose content of lung and spleen deficiency rats were significantly lower than the normal group(P<0.01), there are differences compared with three in the treatment group(P<0.05), Shuganjianpi Yangfei group and spleen nourishing group, Spleen Qi group differences(P<0.05), spleen nourishing group and Yiqi Jianpi group compared with no difference(P>0.05 Shuganjianpi Yangfei), group D- was higher than that of xylose spleen nourishing group and Yiqi Jianpi group. Serum motilin two lung and spleen deficiency rats, gastrin content decreased, there are differences with the normal group(P<0.01), Shuganjianpi Yangfei group and spleen nourishing group, Yiqi Jianpi group compared with difference(P<0.05). The spleen and nourishing lung qi and spleen group compared with no difference(P>0.05), Shuganjianpi Baofei group motilin, gastrin content higher than spleen nourishing group and Yiqi Jianpi group. Bronchial mucosa in two lung and spleen deficiency rats under microscope, edema, inflammatory cell infiltration, pulmonary interstitial hyperplasia of gastric mucosa, edema, inflammatory cell infiltration, the small intestinal villi and the interstitial edema, which were nearly normal after treatment.Conclusion: Chai Weiyi merit scattered, scattered yellow Weiyi, Jiawei Yigong powder can enhance intestinal absorption function, resulting in the increase of the content of D-xylose, can promote gastrointestinal smooth muscle contraction, enhance intestinal peristalsis, the motilin levels increased; can promote the secretion of gastric acid and pepsin, the gastrin level increased; can repair the lung tissue and gastric mucosa and intestinal tissue, improve the symptoms and physical signs of lung and spleen deficiency rats from the whole. Wood Weiyi scattered in increasing serum D-xylose, motilin, gastrin content aspect effect is better than that of yellow Weiyi power scattered and by Jiawei Yigong powder, in the repair of lung, stomach, small intestine no difference. That inhibiting wood and strengthening native gold treatment of lung and spleen deficiency syndrome is better than two efficiency peitushengjin method and spleen nourishing method.