| Objective: In order to explore the relationship between syndrome differentiation in microcosmic level and macroscopic level,and offer the clinical data for making the syndrome differentiation in TCM(Traditional Chinese Medicine)of peptic ulcer more objective and scientific,this study approach the relationship among TCM syndrome types of peptic ulcer and some objective indicators such as the manifestation of gastroscope and the infection of Hp.Methods: The clinical informations of the patients who was in Second Affiliated Hospital of Dalian Medical University during march 2015 and January 2016 were collected in this study and the patients who meet the exclusion criteria were rule out.Then the syndrome of the rest 125 patient was Eedicine clinical research(trial implementation)published by Ministry of Healthstimated with reference to The guiding principles of Chinese medicine new m of China in 2002,and their gastroscope reports were collected by using the type of OLYMPUS GIF-H260 Z gastroscope and the result of Hp checking were came from by 14C-urea breath test or rapid urease test.SPSS 22.0 statistical software was used to entry and analyze the data which has been collected to approach the relationship among different syndrome types of peptic ulcer,manifestation of gastroscope and the infection of Hp.Results:1.The distribution of TCM syndrome types of the 125 patients with Peptic Ulcer included in this research in the order:Liver–stomach hot and suffocating syndrome > spleen-stomach deficiency and heat(cold)syndrome > liver-stomach disharmony syndrome > deficiency of the stomach –yin syndrome.2.The distribution of age in each type of syndrome had statistically significant differences(P < 0.01).The average age of onset of spleen-stomach deficiency and heat(cold)syndrome was much younger than that of the other types of syndrome,and had statistically significant differences with them(P < 0.05 or P < 0.01).The average age of onset of deficiency of the stomach –yin syndrome was much older than the others,and had statistically significant differences with liver-stomach disharmony syndrome and Liver–stomach hot and suffocating syndrome(P < 0.05 or P < 0.01).The cases of males were more than the cases of females in patients of peptic ulcer In the mass.The distribution of structure in each type of syndrome had no statistically significant differences(P > 0.05).3.The distribution of parts classification of gastroscope in order were as follows :duodenal ulcer > gastric ulcer > combined gastric and duodenal ulcers.The distribution of parts classification of gastroscope in each TCM syndrome type had no statistically significant differences(P > 0.05).4.The distribution of the stage under gastroscope in each TCM syndrome type had statistically significant differences(P < 0.01).Deficiency of the stomach –yin syndrome mainly distributed in Scarred stage,had statistically significant differences with the other types of syndrome who mainly distributed in active stage(P < 0.05 or P< 0.01).5.The relationship between the manifestation of lesions and TCM syndrome type :the distribution of moss overlie ulcer lesions in each TCM syndrome type had statistically significant differences(P < 0.05).The distribution of no moss in deficiency of the stomach –yin syndrome was much more than that in the rest three types of syndrome,and had statistically significant differences with them(P < 0.05 or P < 0.01).The distribution of lesions area and the number of lesions in each TCM syndrome type had no statistically significant differences(P > 0.05).6.The relationship between the manifestation of mucosal surrounding the ulcer and TCM syndrome type: the distribution of mucosal erosion in deficiency of the stomach–yin syndrome was less than that in the rest three syndrome,and had statistically significant differences with them(P < 0.05 or P < 0.01).The distribution of converging folds in deficiency of the stomach –yin syndrome was more than that in the other three syndrome types,but had no statistically significant differences in each TCM syndrometype(P > 0.05).The distribution of mucosal congestion and edema in each TCM syndrome type had no statistically significant differences(P > 0.05).7.The condition of combining chronic superficial gastritis,chronic atrophic gastritis and enterogastric reflux in each TCM syndrome type had no statistically significant difference(P > 0.05).8.The distribution of the infection of Hp in deficiency of the stomach –yin syndrome was less than that in the other syndrome types,and had statistically significant difference with spleen-stomach deficiency and heat(cold)syndrome and Liver–stomach hot and suffocating syndrome(P < 0.01).Conclusions:1.TCM syndrome type distribution in the order :Liver–stomach hot and suffocating syndrome > spleen-stomach deficiency and heat(cold)syndrome >liver-stomach disharmony syndrome > deficiency of the stomach –yin syndrome.The distribution of parts classification of gastroscope in order were as follows:duodenal ulcer > gastric ulcer > combined gastric and duodenal ulcers.2.Age was associated with TCM syndrome type of peptic ulcer.There was no relationship between gender and TCM syndrome differentiation of peptic ulcer.3.There was some correlations between the manifestation of gastroscope and TCM syndrome differentiation of peptic ulcer,.deficiency of the stomach –yin syndrome different from the other syndromes.4.The infection of Hp was associated with TCM syndrome differentiation of peptic ulcer. |
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