Study On TCM Syndrome Differentiation And Regulation Of Peptic Ulcer During Active Period

Objective:To explore the character regularity of TCM syndrome, syndrome differentiation, and using situation of drugs of ulcer disease through the retrospective study of medical records in patients with active peptic ulcer, in order to provide future clinical and research reference.Method:It consisted of two parts:(1)Literature research:To explore the etiology, pathogenesis and syndrome differentiation of TCM and etiology, pathogenesis and treatment of modern medicine in patients with active peptic ulcer by reviewing the literature in recent years.(2)Clinical research:Collected medical records of inpatients with active peptic ulcer in Sichuan Province TCM Hospital, and analysis them with SPSS19.0software.Result:1.187copies of medical records were studied, including DU117cases, GU46cases, CU24cases.131males and56females were included; and male to female ratio is2.3:1.2. The age was distributed in a nearly normal fashion.3. Males had higher rates of smoking and alcohol using.4. The maximum number of cases was occurred in the fall, and the emergence of a peak was occurred at the end of autumn.5. Predisposing factors included the following aspects:no obvious incentive, dietary factors, alcohol, drugs, fatigue, emotional. Except no obvious incentive, the dietary factors account for up to scale.6. HP positive rate was64.2%.7. Frequency of the syndrome appeared as followed:stomach collateral stasis syndrome<stomach yin deficiency syndrome<cold and heat incomplexity syndrome<liver and stomach heat syndrome<liver-stomach disharmony syndrome<spleen-stomach weakness syndrome. The type, size and HP infection of ulcer had no obvious correlation TCM syndromes. The liver-stomach disharmony syndrome and the stomach yin deficiency syndrome were common in the HP-negative group; while the liver and stomach heat syndrome, the liver-stomach disharmony syndrome and the cold and heat in complexity syndrome were common in HP-positive group. The spleen-stomach weakness syndrome was common in both groups. HP infection rate was highest in the liver and stomach heat syndrome, and lowest in stomach yin deficiency syndrome.The spleen-stomach weakness syndrome was most common in ulcer diameter less than0.5cm group, the liver and stomach heat syndrome was most common in ulcer diameter large than1.0cm group, the liver and stomach heat syndrome and the spleen-stomach weakness syndrome ware most common in ulcer diameter large than0.5cm group.8. Jin ling zi san, Chai hu shu gan san were used in the treatment of the liver-stomach disharmony syndrome. Liu jun zi tang, Xiao Jian Zhong tang, Li zhong tang were used in the treatment of the spleen-stomach weakness syndrome; Zuo jin wan, Qing zhong tang were used in the treatment of liver and stomach heat syndrome, Shao yao gan cao tang, Mai dong tang, Yi wei tang were used in the treatment of stomach yin deficiency syndrome, dan shen yin, Shi xiao san were used in the treatment of the stomach collateral stasis syndrome, Ban xia xie xin tang were used in the treatment of the cold and heat incomplexity syndrome.Conclusion:1. Incidence of male was higher than female, which may be associated with smoking, drinking and other related bad habits.2. The type, size and HP infection of ulcer had no significant correlation with TCM syndromes. The spleen-stomach weakness syndrome was the most common type. Invigorating spleen qi is the basis of treatment, while the treatment method of moving qi, activating blood and resolving stasis was used throughout all the syndromes.