Research On Three-dimensional Printability Of Alginate Structure

3D printing is now widely applied in the electronics, automotive, aerospace, medical engineering and other fields. Thanks to its high precision, high efficiency for single product, convenient operation, it recently got more and more attention from the whole word. In recent years, the technology has been gradually applied into the tissue engineering, in order to achieve the cultivation of human tissues in vitro with the cell of ill which can be approached to reduce danger of organ transplant rejection. Biological hydrogels dimensional printing is a tissue processing method to deposit natural materials with complex morphology. The three-dimensional scaffold structure determines nurture morphology and growth characteristics of cells after printing. It seems clear that the three-dimensional biological hydrogel printable study have great significance in biological tissue engineering.Based on the analysis of the characteristic of biological hydrogels dimensional printing, the paper developed hydrogel material configurations for high precision printing. Insulation, cooling and other special features of the three-dimensional hydrogel print platforms have been designed during research. From the plane ID, 2D to 3D structure of the three-dimensional gel scaffold. The article gradually improves the study of process parameters. It includes:(1) Material configuration of hydrogel printing. The article has studied the ratio of water-soluble gel stock solution for sub millimeter hydrogel structure, which came from the desired viscosity, mechanical structure and moisture conditions.(2) To achieve the special case of a hydrogel structure prints, a unique 3D platform architecture has been designed, including parts and accessories main platform design, module design such like insulation fixtures, refrigeration platform module, bath platform module and many other auxiliary modules. The 3D platform has been deeply repeated for the high-precision printing.(3) The study for the hydrogel flat printing process parameters has been made, starting from the modeling point of impact on the research process parameters print modeling points. And gradually started to study a one-dimensional line printing process parameters influence of process parameters on linear line width and diffusivity. According to the structure of theoretical analysis and experimental results, the ideal process parameters have been given out and the method and improvements of the parameters have been stated alongside. The result is still reference significance for other biological materials.(4)Through the three-dimensional structure layer film print, the article analyzed and studied the relationship between layer membrane mechanical strength of structure and process parameters. The article gave out the range of data for kinds of special occasions and fill patterns. In order to solve the decrease caused by increasing of film layers, the article suggest a method for optimization with hardener atomization process. The process parameters for longitudinal feed have been determined by longitudinal feed theoretical analysis and experimental research. The minimum interval between the layers at room temperature at 25℃ has also been shown. According to the 3D model test at last, all of the process parameters have been proved and both problems encountered and prospect are summarized in the final.