Study On Multi-scale Modeling Of The Femoral Prosthesis And Biomechanics Analysis

The coloboma of femur caused a great number of inconveniences to the patients’ life and works that result from disease, trauma or any other reasons. In order to recover the function of the body of patients, the medicine personals have proposed a variety of different methods successively. And, the artificial prosthesis repair technology has been considered to be the most effective method for all kinds of bone defect and joint disease at the later period, however, with in-depth clinical research, this method also exposed some problems, such as:soft-tissue penetration, and infection, prosthesis loosening or broken and so on. According to the statistics, aseptic loosening of prosthesis is one of the most common problems in the surgery, with an occurring about7%-30%.For the problem of prosthesis’aseptic loosening, this paper put forward a multi-scale modeling method for the prosthesis based on CT images, aiming at enhancing the matching property of the prosthesis to the bone tissue, reducing the influence of the prosthesis to distribution of stress in femur, and finally radically reduces the possibilities of loosing.This paper mainly covers the following aspects:(1) In consults a great number of related literature, it systematically elaborated the latest research progress of the internal structure, mechanical properties and reconstruction theory of human bone and analyzed the mechanism for aseptic loosening of prosthesis based on the theory of the adaptive remodeling for bone tissue, which provides a theoretical basis for follow-up study.(2) Introduced the reverse engineering into reconstruction process of human skeleton that widely applied in engineering field, established the3D CAD model of human hips based on medical CT images, carried a simulation for the repair surgery in Mimics, and finally obtained the required macroscopic model of prosthesis.(3) Based on medical CT images, established the multi-scale CAD model of the tissue engineered prosthesis that can be manufactured by rapid prototype machines, radically improving the matching property of the prosthesis to the bone tissue in biomechanics aspects.(4) Carried a static analysis for the model of complete femur and defect femur, as well as several prosthesis-femur assembly model in ANSYS, confirmed the feasibility of the proposed multi-scale modeling method in improving the matching property of the prosthesis to bone tissue, providing a theoretical basis for further optimizing the prosthesis model.