TCM Syndrome Type Distribution Of Coronary Heart Disease Association With Anxiety Depression And The Relative Factors Analysis

Objective:Through investigation the Traditional Chinese Medicine (TCM) syndrome type disribution about Coronary Heart Disease (CHD) with anxiety and depression, analysis the differences and correlations with the severity of coronary artery stenosis and risk factors in patients with CHD. to improve the recognization and provide theoretical reference for the clinical syndrome differentiation and follow-up study of the disease.Methods:1. Analysis the CHD with anxiety depression patients, grouped according to the result of coronary angiography, anxiety depression rating scale, CHD risk factors. Analysis the degree of coronary artery stenosis, including single vessel, double vessel and triple vessel lesions. Anxiety depression rating scale including slight, moderate, severe state. Risk factors including hypertension, diabetes, dyslipidemia, smoking.2.With reference to the "Expert Consensus about TCM Diagnosis and Treatment of Anxiety Depression Before and after Percutaneous Coronary Intervention (PCI)", divided CHD with anxiety depression into eight kinds of compound types. According to the clinical quantitative scale to develop TCM syndrome scoring criteria. Analysis the correlation of TCM syndrome type distribution.Results:1. CHD with anxiety had 201 cases (67.9%); CHD with depression had 161 cases (54.4%); CHD with anxiety depression had 66 cases (22.3%).2. In the groud of CHD with anxiety, the type of qi zhi tan yu had 65 cases (32.3%), gan yu qi zhi had 44 cases (21.9%), qi zhi xue yu had 31 cases (15.4%). qi yu hua huo had 24 cases (11.9%). xin pi liang xu had 14 case (7.0%). xin dan qi xu had 10 cases (5.0%). yin xu gan yu had 9 cases (4.5%). gan dan shi re had 4 cases (2.0%). In the groud of CHD with depression, the tye of qi zhi xue yu had 54 cases (33.5%). gan yu qi zhi had 30 cases (18.6%). qi zhi tan yu had 19 cases (11.8%). yin xu gan yu had 14 cases (8.7%). qi yu hua huo had 13 cases (8.1%). xin pi liang xu had 13 cases (8.1%). xin dan qi xu had 12 case (7.5%). gan dan shi re had 6 cases (3.7%). Suggest that higher percentage of excess syndrome in the two grouds.3. In the groud of CHD with mild and morderate anxiety, the type of qi zhi tan yu, gan yu qi zhi and qi zhi xue yu had higher proportion. In the groud of CHD with severe anxiety, the type of xin pi liang xu type and xin dan qi xu had higher proportion.In the groud of CHD with mild and moderate depression, the type of qi zhi xue yu, gan yu qi zhi and yi xu gan yu had higher proportion. In the groud of CHD with severe depression, the type of xin pi liang xu and xin dan qi xu had higher proportion. Suggest that excess sydrome may maily in the groud of mild and moderate state, deficiency syndrome may maily in the groud of severe state.4. Different TCM syndrome type of CHD with anxiety, the anxiety score different (X2=88.450,P<0.05). Different TCM syndrome type of CHD with depression,the depression score different (X2=78.148,.P<0.05).In both groud, the type of xin pi liang xu had the highest score, and then type of xin dan qi xu,gan yu qi zhi had the lowest score, and then type of qi zhi tan yu and qi zhi xue yu.5. Different ages of CHD with anxiety and depression, different distribution of TCM sydrome. had statistical significance (P<0.05). In the groud of CHD with anxiety, under the age of 59 and the age of 60 to 69 had higher proportion in the type of gan yu qi zhi and qi zhi tan yu, the age of 70 to 79 had higher proportion in the type of qi zhi tan yu and xin pi liang xu. In the groud of CHD with depression, under the age of 59 and the age of 60 to 69 had higher proportion in the type of gan yu qi zhi, qi zhi xue yu and qi zhi tan yu, the age of 70 to 79 had higher proportion in the type of qi zhi xue yu and xin pi liang xu.6. The degree of CHD with anxiety had correlation with coronary lessions (r=0.304.P<0.05). The degree of CHD with depression had correlation with coronary lessions (r=0.241,P<0.05). Single and double vessel disease mainly in mild-moderate anxiety and Depression; three or more vessel disease mainly in severe anxiety and depression.7. The risk factors in both CHD with anxiety and depression had no significance difference (P>0.05). In the two groud,the highest proportion of hypertension.followed by diabetes, and then dyslipidemia and somking. The risk factors had correlation with CHD with anxiety (r=0.302.P<0.05). The risk factors had correlation with CHD with depression (r=0.253.P<0.05). None risk factor or one to two risk factors mainly in mild-moderate anxiety and depression; three or more risk factors mainly in severe anxiety and depression.Conclusion:1.Anxiety state may be more common in CHD association with psychological disorders.2.Different degree of CHD with anxiety and depression, the TCM syndrome different.As with degree increase, the lesion from excess syndrome change to deficiency syndrom, to provide reference for clinic treatment based on defferentiation.3.Different ages of CHD with anxiety and depression, the TCM syndrome different. With increase of ages, the lesion may turn excess sydrome to deficiency-excess complication.4.Different degree of CHD with anxiety and depression had correlation with coronary lessions. With increase of coronary lessions. the degree of anxiety and depression increase.5.Different degree of CHD with anxiety and depression had correlation with risk factors. With increase of risk factors, the degree of anxiety and depression increase.