The Clinical Research Of Needle-warming Moxibustion Of Mild And Moderate Diabetic Gastroparesis Patients And Its Influence On Serum Leptin

Objective:by observing the needle-warming moxibustion on diabetic gastroparesis (DGP) in patients with clinical symptoms and the influence of serum leptin to explore the needle-warming moxibustion can improve gastric emptying of DGP patients, It also can be used to discuss the needle-warming moxibustion can affect the level of DGP patients’serum leptin and the mechanism of needle-warming moxibustion in the treatment of DGP.Methods:59 cases of diabetic gastroparesis patients were randomly divided into warm acupuncture group and the control group.Warm acupuncture group refers to DGP patients with insulin hypoglycemic therapy and needle-warming moxibustion therapy which is carried out once per day.There are total 15 times to emplement this therapy;The control group refers to DGP patients only with insulin hypoglycemic therapy.Two groups of DGP patients treatment for 2 weeks.We should We should determine the level of DGP patients’serum leptin of these two groups when we start and finish this process. What’s more,the determinations of the level of health people’serum leptin are necessary.DGP patients of these two groups must fill in diabetic gastroparesis symptoms rating scale and the diagnosis table of DGP patients’classification before and after treatment.Results:1, the total effective rate and curative effect index of warm acupuncture group are higher than the control group, and the differences are statistically significant (P< 0.05)2. Compared with the serum leptin of DGP patients of warm acupuncture group before the treatment,the serum leptin of DGP patients after the treatment significantly decreased (P< 0.01).3.Compared with the serum leptin of DGP patients of the control group before the treatment,the serum leptin of DGP patients after the treatment significantly increased (P< 0.01).4.The serum leptin of DGP patients of warm acupuncture group before and after the treatment are obviously higher than the level of health people’serum leptin (P<0.05); The serum leptin of DGP patients of control group before and after the treatment are obviously higher than the level of health people’ serum leptin (P<0.05).5. Comparision among the serum leptin of DGP patients of warm acupuncture group before the treatment and the serum leptin of DGP patients of control group before the treatment, there was no statistically significant difference (P> 0.05). the serum leptin of DGP patients of warm acupuncture group after the treatment were significantly higher than the serum leptin of DGP patients of control group after the treatment(P<0.05).Conclusion:1, The needle-warming moxibustion an significantly improve the symptoms of diabetic gastroparesis, and curative effect was better than insulin hypoglycemic therapy alone.2. The needle-warming moxibustion is safe and effective in the treatment of DGP.3. The level of serum leptin of diabetic gastroparesis patients are far higher than that of normal people, the needle-warming moxibustion can reduce the level of serum leptin of DGP patients, but it can’t drop to normal or near normal,but the insulin therapy increases the level of serum leptin of DGP patients.4. The needle-warming moxibustion can obviously improve the symptoms of diabetic gastroparesis, which may use this approach:reducing the level of serum leptin of DGP patients.