Analysis Of Prevalence And Related Factors Of Depression After Acute Cerebral Stroke

Objective: Post-stroke depression(PSD) is probably the most common emotional disturbance, and is associated with increased disability, and poor functional and cognitive outcomes in stroke survivors. PSD has a negative impact on rehabilitation processes, and affects functional recovery, cognitive function, quality of life and healthcare use of stroke survivors. Emotional disturbances can be observed, not only in disabled stroke patients, but also in those who are perceived to be functionally independent in their activities of daily living. PSD also increase the risk of falls in stroke survivorsMethods: The patients who suffered from the original situations about type of stroke, lesion locations, neurological function score, hypertension, heart disease, diabetes, dyslipidemia, hyperuricemia, high fibrinogen and related laboratory indexes etc.,had been investigated at the hospital of Jilin province during Oct. 2014 to Jun. 2015. We used to Hamilton Depression Rating Scale(HAMD) scores, assessed the severity of depression and adopted NIHSS(National Institute of Health stroke scale) evaluation of the degree of neurological impairment. Then the survey data were analyzed by Epidata3.1 and applied to SPSS20.0 statistical software.Results:(1)We have investigated 120 patients’ cases of acute stroke with 45.8% depression prevalence; including 32 cases at sight level, accounting for 26.7%; including 15 cases at moderate level, accounting for 12.5%; including 8 cases at severe level, accounting for 6.6%.(2)The prevalence of depression in stroke patients with obesity, hypertension and diabetes mellitus was significantly higher than those without vascular risk factors(P<0.05).(3)The prevalence of depression was different from different lesion sites. The prevalence of depression was higher than that of the brain stem and thalamus, and the prevalence of depression with multi lesion was significantly higher than single lesion in patients with cerebral apoplexy(P<0.05).(4)Post stroke depression has relation to the neurological severity. NIHSS high score at admission is more prone to depression(P<0.05).(5)The hypersensitive C-reactive protein(hs-CRP) was significantly associatedwith post stroke depression. By logistic multiple factors regression analysis, the prevalence of cerebral stroke depression had closely associated with lesion site, hypertension, overweight and obesity, admission NIHSS score.Conclusions: The symptoms of depression after acute stoke often occur. Mild and moderate PSD are more common. The prevalence of depression in patients after acute stoke is related to the risk factors of obesity, hypertension, diabetes and other vascular risk factors, stroke lesion location and multiple lesions, neurological function defect severity, hs-CRP, etc.