Yu Shang Liquid Stasis Arthritis Clinical Research Type Knee Osteoarthritis

Objective:Incidence of knee osteoarthritis in recent years showed a trend of rising year by year, the high rate of morbidity, teratogenic, given that there is no good preparation and method of this topic research callus emulsion preparation process and treatment of blood stasis blocking type of knee osteoarthritis clinical efficacy, to hope for the treatment of blood stasis blocking type of knee osteoarthritis method for determining the standards, to provide clinical basis.Methods:(1) the clinical application has curative effect of callus cream, through the orthogonal experiment design method, adopt the modern extraction and separation methods and emulsion preparation technology, made from callus emulsion; In order to better control quality, provide scientific basis for the preparation process.(2) in 60 patients were randomly divided into control group and treatment group. Control group for paishi topical treatment, treatment group for callus emulsion combined with massage treatment, compared before and after treatment between two groups of clinical symptoms integral, pain score and serum NO index before and after the change. All data on the computer SPSSl7.0 version package is adopted to improve the analysis, the data obtained by( x + s) said, count data of gender, efficient with chi-square test, measurement data before and after their own with paired t test, t test between groups, between different groups which with no statistical significance, P > 0.05, P < 0.05 significance, P < 0.01 said there is a very significant meaning. Watch the pros and cons of two groups of patients.Results:1. Through orthogonal experiment, using 60% ethanol concentration, dosage of ethanol for 10 times, reflow 2 h, back three times, as the best preparation technology. Emulsion preparation program for: take west tragacanth gum Arabic 2.7 g, 2.7 g dry mortar, study well, add liquid paraffin 9 ml, slightly uniform grinding, joining the alcohol extract and the frankincense myrrh powder, grinding for uniform dispersion. One-time add 6 ml distilled water, quickly towards a grinding made of colostrum. Add water right amount, mix for a quick.2. Symptoms integral comparison: two groups of patients with symptoms integral are improved compared with before treatment, after statistics analysis after treatment compared with before treatment there is a very significant difference(P < 0. 01), the treatment group compared with control group has a very significant difference(P < 0. 01).3. The pain score comparison: pain scores compared with before treatment in both groups were improved better, after statistics analysis after treatment compared with before treatment there is a very significant difference(P < 0.01), the treatment group compared with control group with significant difference(P < 0.05 or P < 0.01);4. Serum NO index comparison: serum NO index compared with before treatment in both groups were improved better, after statistics analysis after treatment compared with before treatment there is a very significant difference(P > 0.05), the treatment group compared with control group, NO statistical significance(P > 0.05).Conclusion:1. This study callus emulsion preparation technology correctly, can better control the quality, provide scientific basis for the preparation process, should be in the clinic.2. The callus emulsion treatment of knee osteoarthritis in the improvement of pain and symptoms in patients have good curative effect, can be used as a common treatment reference in similar diseases.