Research On The Relationships Between Children Obesity And Recurrent Pneumonia

Background: In 1999, the obesity was formally defined as a disease by the World Health Organization(WHO); a series of global human health hazards caused by obesity are still plaguing the entire medical profession. Currently, obesity has become one of the four medical social problems such as alcoholism. The question is even more troubling that the incidence of obesity in Children is increasing year by year, so obesity and its related complications pose a serious threat to health of children and adolescents worldwide. Pneumonia, one of the most common childhood respiratory diseases around the world, is also one of the main causes of death among children in developing countries. With factors changes in the living environment and living conditions, the incidence of Children with recurrent pneumonia is increasing year by year, which has brought great harm to children’s physical health, but also caused a burden on society and family. During the clinical work process, obese children compared with normal-weight children are more susceptible to be infected with respiratory diseases, especially recurrent pneumonia. It will provide practical clinical significance for the prevention of recurrent pneumonia by research on the relationships between obese or overweight history and recurrent pneumonia.Purpose: In this study, we carried out analysis on obesity factors and its relationships with recurrent pneumonia according to the data regarding Children with recurrent pneumonia(No significant underlying diseases) collected in pediatric inpatient department of the Second Affiliated Hospital of Dalian Medical University from January 2014 to January 2015. And this research shall provide some advices to reduce the incidence of children with recurrent pneumonia and realize early prevention.Materials and methods:By analyzing the data collected from 102 cases(Experimental Group, No significant underlying disease) and 102 cases that have been infected with pneumonia for one time(Control Group, No significant underlying disease) in pediatric inpatient department of Second Affiliated Hospital of Dalian Medical University from January2014 to January 2015, we found the differences between children’s age and gender was not statistically significant, and BMI differences between the two groups was statistically significant. So we analyzed risk factors for children with recurrent pneumonia by χ2 univariate test and multivariate logistic regression model methods.Results:1. The analysis results of χ2 univariate test:The number of overweight and obese children in the Experimental Group accounted for 36 cases, and 20 cases in the Control Group; the number of children with allergies history in the Experimental Group accounted for 61 cases, and 41 cases in the Control Group; the number of children with asthma history in the Experimental Group accounted for 57 cases, and 31 cases in the Control Group; the number of children with Neutropenia syndrome in the Experimental Group accounted for 48 cases, and 25 cases in the Control Group; Immunological tests showed that the number of children with low IgG in the Experimental Group accounted for 37 cases, and 15 cases in the Control Group and the number of children with high IgG in the Experimental Group accounted for 63 cases, and 39 cases in the Control Group. Experimental results showed that differences of obesity or overweight, allergies history, asthma history, Neutropenia syndrome, lower IgG and higher IgE between Experimental Group and Control Group have statistical significance. Other risk factors: the differences of Mycoplasma pneumoniae antibody positive history, EB virus antibody positive history, history of eczema, preterm birth, breastfeeding history, immunological parameters(lower IgM and IgA CD4/CD8<1) between Experimental Group and Control Group do not have statistical significance.2.The multivariate logistic regression analysis:It shows that Obese or overweight and allergies factors are independent risks to cause recurrent pneumonia after 5 variable regressions selected from χ2 univariate testanalysis including proportion of obese or over-weight, allergies history, asthma history and low immunity were analyzed.Conclusion:1. Recurrent pneumonia for Children with no significant underlying diseases iscaused by interaction of multiple factors;2. Obese or overweight and allergies factors are independent risks to cause recurrentpneumonia;...