Clinical Observation On The Treatment Of Type Subacute Thyroiditis With Zi Yin Qing Re

Objective: To observe the Yin heat method in combination with small dose of hormone treatment of subacute thyroiditis disease clinical curative effect, try from hormone dosage, blood sedimentation, duration, recurrence rate and efficiency in the short term to explore its action mechanism, as to provide theoretical basis for traditional Chinese medicine in the treatment of subacute thyroiditis.Methods: Collection of 48 patients with the diagnosis of subacute thyroiditis, randomly divided into treatment group and control group, each group 24 cases. Control group using western medicine prednisone treatment, treatment group on the basis of heat type, the formulas used ziyin medicine 8 weeks, observe two groups after the drug was stopped before and after treatment the change of the main symptoms and signs, treatment before and after the change of blood sedimentation, and evaluation of hormone dosage, course length, the total effective rate and 12, 16 weeks after discontinuation of relapse.Results: The observation of ziyin small heat method that hormone treatment of subacute thyroiditis safety usage and curative effect of disease. TCM symptoms comparison: in goiter, thyroid pain, sore throat, fever, dry throat dry mouth on the ease of group comparison before and after treatment, P < 0.01, significant differences, indicated that both groups can significantly relieve the above symptoms, between groups after treatment, P < 0.01, significant differences, on the basis of a single hormone and nourish Yin heat drugs more than simple application hormone can effectively alleviate the symptoms; Hormone dosage analysis: the treatment group of 2040 mg, the control group of 3240 mg, the treatment group than the control group on the dosage of hormone 1200 mg, less heat method combined hormone dosage instructions ziyin than simple application dosage of hormone therapy significantly reduced; Blood sedimentation analysis: before treatment the treatment group the average blood sedimentation 43.04 + /- 11.59 mm/h, control group 42.33 + /- 9.88 mm/h, average blood sedimentation after treatment thetreatment group 6.04 + /- 1.57 mm/h, control group 8.62 + /- 2.30 mm/h, blood sedimentation after treatment group analysis of blood sedimentation analysis between group P < 0.01, P < 0.01, there was a significant difference, the traditional Chinese medicine combined hormone and simple application of hormones can reduce blood sedimentation, through the statistics on the basis of a single hormone and nourish Yin heat drugs is better than a single hormone can reduce blood sedimentation; About 7.00 + /- 1.31 weeks in duration analysis: the treatment group and control group is about 8.83 + /- 1.55 weeks, less 2 weeks duration of the treatment group than the control group; explain ziyin heat method combined hormone therapy can shorten the duration of symptoms, reduce the dosage of hormone; Total effective analysis: the treatment group the total efficiency of 100%, total effective rate 79.2%, the control group(P < 0.01, significant differences of ziyin hormone heat method is superior to the simple application of hormone treatment of 13 cases of treatment group clinical control, the control group, 8 cases illustrate ziyin heat method combined hormone better able to cure the disease; Recurrence analysis: stop drug treatment group 4.1% recurrence rate 0 and 16 th weeks, 12 weeks after 12 weeks of stop drug control group 16.7%, 29.2% for 16 weeks, statistics analysis(P < 0.01, significant differences of ziyin hormone heat method that can reduce the relapse after drug withdrawal, hormone effect is more significant than simple applications.Conclusion: Using ziyin small heat method that hormone treatment of subacute thyroiditis disease can obviously reduce the patient’s subjective symptom and signs, ziyin heat found by statistical method combined hormone therapy can effectively reduce the dosage of hormone, reduce the side effects brought by hormone, shorten clinical course, reduce blood sedimentation, reduce the recurrence rate, its mechanism of action is worth clinical research to explore further.