Clinical Efficacy Research Of Using Huagaisanjiawei Decoction To Treat Cough Variant Asthma Which Belongs To Wind-excess And Bronchia Spasm Syndrome

Research Objective:Observe and evaluate the efficacy and safety of using Huagaisanjiawei Decoction to treat cough variant asthma which belongs to wind-excess and bronchia spasm syndrome. Provide clinical evidence for the study of Chinese medicine treatment of CVA.Research Methods:There were48cases with meet the diagnostic criteria of cough variant asthma of wind-excess and bronchia spasm syndrome devided into observation group and comparable group by order at random, both the quantity is24, to compare the two groups by before and after treatment in each group, the observation group treated on the montelukast pills and huagaisanjiawei tang, and the comparable group treated on the montelukast pills, two weeks for a course of treatment, by comparing and analysising the cough score, the TCM syndrome integral and effective rate, the number of EOS, pulmonary function (FEV,%, PEF%). All the date was analyzed by SPSS22.0software.Results:(1) Comparison of cough scores:the comparison between period and after treatment in both group respectively has statistical different (P<0.01); the comparison between2groups after treatment has statistical difference (P<0.01);(2)Comparison of the TCM syndrome integral:the comparison between prior and after treatment in both group respectively has statistical difference (P<0.01), the Comparison between the2groups has statistical difference (P<0.01); Comparison of total effective rate according to TCM syndrome integral:87.5%for treatment group, and54.2%for control group respectively, the different has significant difference (P<0.05);(3)Comparison of the number of EOS:the comparison between prior and after treatment in both group respectively has no statistical difference (P>0.05), the Comparison between the2groups has no statistical difference (P>0.05); (4) Comparison of Pulmonary function (FEV1%, PEF%):the comparison between prior and after treatment in both group respectively has statistical difference (P<0.05), the Comparison between the2groups has statistical difference (P<0.05);(5)During the period of treatment, all patients of two groups have no adverse drug reaction.Conclusion:Huagaisanjiawei Decoction can improve the clinical control rate of CVA, improve clinical symptoms and improve lung function in patients. There was no adverse reaction during the treatment, the safety evaluation is I. Effective, safe, worthy of promotion in clinical use.