The Clinical Observation Of Wind Evil Encroach Lung-type Cough Variant Asthma That Treatment Of Ke Ping Tang

Objective:To observe the effect of treating Wind evil encroach lung -type cough variant asthma with ke ping tang united conventional treatment of western medicine and western medicine treatment,comparison of the two effects,With the effects of Cytokines IL-13 and the target of Pulmonary function-the largest peak expiratory flow,Discussion of Chinese medicine treatment of cough variant asthma General advantages,Cytokines involved in the pathogenesis of IL-13 regulation of the advantages and the improving situation Of pulmonary function.Information and methods:1.Selection wind cough disease traditional Chinese medicine belong to Wind evil encroach lung-type,andReference to Western diagnostic criteria of CVA,Select 60 cases of patients,and according to traditional Chinese medicine dialectical standard classification for randomly divided into traditional Chinese and western medicine and western medicine treatment of 30 cases of control group.2.Both groups were given Shu li die(50/100) inhalation treatment,Treatment group at the foundation of western medicine on the use of add Hirayu with the treatment of cough, Compared clinical efficacy of the two groups,Detection of two groups before and after treatment in the largest PEF,Numerical of IL-13,Change of dosage about determination of bronchial provocation test,In the course of 4 weeks after the end of follow-up cases of recurrence of the number of cases cured.3.Statistical treatment:SPSS13.0 statistical software used for the United States the results of statistical treatment,Set for P≤0.05 statistically significant difference.(1) pre-treatment comparability analysis(2) Group matching t test before and after treatment(3) group into a group t test(4) Level of information using chi-square test,Level count data using rank sum test,Comparison of the rate of adoption of the U test.Results:1.Clinical Observation:Comparison of TCM Syndromes points and General efficacy, The two groups before and after treatment within each group of points compared syndrome were significantly statistical significance(P＜0.01),Two groups before and after treatment comparison points TCM Syndrome have decreased significantly.The two groups after treatment of TCM Syndrome margin points and difference between two points were no significant differences(P＞0.05),General effects of the two groups no significant difference (P＞0.05),The efficiency of the two groups after treatment significantly higher than those of comparison group slightly.2.The intervention of ke ping tang on the cytokine IL-13:Compared the two groups before and after the treatment group,IL-13 values,Two groups after treatment and difference after treatment were all significant differences(P＜0.01),Lower levels of IL-13 treatment group was significantly better than the control group.3.The intervention of ke ping tang on PEF:Compared the two groups before and after the PEF treatment group is expected to account for the value of the percentage of value,PEF between the two groups are expected to account for the value of the percentage difference between the value and treatment comparison,Were all significant differences(P＜0.01),PEF improvement in the treatment group was significantly better than the control group.4.The intervention of ke ping tang on airway hyperresponsiveness(Determination of BHR cases dosage Level):The two groups after treatment dosage level of BHR,compared to the situation there is statistically significant difference(P＜0.05),The two groups dosage level of BHR's difference before and after treatment is significant differences Treatment group, airway hyperresponsiveness significantly lower than the control group.5.Two cases of recurrence after treatment follow-up compared to the situation:Cured two cases of recurrence after 4 weeks follow-up compared to the situation there is statistically significant difference(P＜0.05),The number of recurrent cases of the treatment group than the control group.6.The course of the treatment group did not find obvious side effects,0 cases of test subjects during the exit.Conclusion:1.Improvement of TCM Syndromes points and General aspects of efficacy to determine,after 4 weeks the treatment of TCM Syndrome General effects of integration The two groups had no significant difference,But follow-up cases of recurrence of the number of cases cured at 4 weeks after the end of treatment,Western medicine treatment of simple cases of the control group recurrence was significantly more than the treatment group,Description that help with Western medicine Wind evil encroach lung-type cough variant asthma treatment effective,And a significant reduction in recurrence rate after cessation of medication.2.A significant reduction in the level of IL-13,improving the level of PEF,With the determination of BHR Change dosage,The treatment group was significantly better than the control group,western medicine alone,Description that ke ping tang to reduce airway responsiveness,inhibition of cytokines involved in the pathogenesis and reduce airway inflammation there is synergy.Maybe are one of the mechanisms of Qufeng Xuanfei,Liyan Yang Jin traditional Chinese medicine.3.ke ping tang has obvious security and effective on Community-acquired pneumonia.