Analysis And Evaluation Of Trace Elements In Peripheral Blood Of Pregnant Women And Infants At Linyi

Despite of the low content in human body, trace elements participate in all kinds of physiological metabolism process, serving as important component of metalloenzyme and cofactor activating enzyme activity, and they are essential, for human body. Growing infants demand much more trace elements to meet their physiological needs due to their thriving metabolism process. Similarly, pregnant women are easily lack of trace elements. This is because growing infants need to absorb enough nutrition from mother. However, normal diet can hardly supply enough trace elements to pregnant women. Trace elements are critical to fetation, shortage or surplus will influence the differentiation and development of embryo, resulting in congenital malformation or abortion.Lead is a heavy metal element with neurotoxicity, having no positive effects on human health. The concentration of lead in human blood should be zero in ideal state. Research demonstrated that the rising lead concentration in human blood can slow the growth of embryo through embryonic barrier, leading to the dystrophia of offspring’s nervous system. From this, exposure to lead in foetal period is much worse than in infancy. The common effect of lead on infant’s intelligence appears as neurotoxicity. Detection and analyze the content of peripheral blood toxic lead in certain area is an important method to figure out the lead level in pregnant women and infants.In order to know the content of five essential trace elements (Ca, Fe, Zn, Mg and Cu) and toxic elements (Pb, Cd) in pregnant women and infants bodies at Linyi, data of peripheral blood trace elements and blood lead level of pregnant women and infants with various ages in recent years was collected and analyzed. Understanding whether there exists exceptional ingestion of trace elements and overhigh level of blood lead in pregnant women and infants’ body now in this area, will further lay the foundation of prophylactico-therapeutic measures regarding different factors. The analyzing work consists of the following three aspects.1) Overall distribution of single trace elements, conducting large sample trends description and analyze for single trace elements.a) Conducting overall large sample description of the content of every trace element for pregnant women and infants, respectively. Evaluating the abnormal distribution and mean shift of some trace elements between two groups in this area.b) Evaluating the distributional difference of single trace element between two groups. Analyzing the inborn and acquired internal connection of trace elements between pregnant women and infants.2) Conducting statistical analysis of abnormal ratios of single trace elements, comparison and description of age and gender with abnormal distribution concentration of trace elements.a) Conducting variance analysis of trace elements between various infant age groups, evaluating the interaction between various age group factors.b) Conducting t test of trace elements between sex groups, evaluating the interaction between sex group factors.3) Conducting statistical correlation analysis of the content of two or more trace elements, analysis and description of the relationship between abnormal distribution and interconnected relationships of trace elements.