The Prevalence Of Isolated Systolic Hypertension In Adult Populations From The Han, Uygur And Kazakh Ethnic Groups In Xinjiang, China

Objective:To estimate the current prevalence and epidemiology of isolated systolic hypertension (ISH) among adult populations from different ethnic groups in Xinjiang province and to further establish a theoretical basis for developing personalized therapeutic strategies for hypertensive populations. Methods:To analyze the prevalence and risk factors of ISH in different ethnic groups in Xinjiang province, a cluster sampling method was adopted to conduct a cross-sectional study on people aged 35 years and older from the Han, Uygur, and Kazakh populations in the Urumqi, Kelamayi, Hetian, Zhaosu, Fukang, Tulufan and Fuhai. Results: A total of 14,618 adults were surveyed with a response rate of 88.80%. The overall prevalence of ISH was 11.95% (men:10.84%vs. women:12.92%); the prevalence of ISH in women was significantly higher (x2=15.06, P=0.00) than that in men. The prevalence varied significantly with age (x2=822.71, P=0.00) and increased in the elderly (x2=769.59, P=0.00). A logistic regression analysis revealed that age, obesity, diabetes, and dyslipidemia are major risk factors for ISH; patients with hypertension combined with obesity or diabetes are at a high risk of ISH. Conclusions: The prevalence of ISH in Xinjiang is higher than average and exhibits a gender difference. There is a trend of increased prevalence with increasing age. Populations with obesity, diabetes, or dyslipidemia and patients who have hypertension combined with obesity and/or diabetes should be aware of early preventive interventions.