Clinical Analysis Of 5357 Hospitalized Patients With Chronic Heart Failure In Xinjiang Of China

Objective:We aimed to investigate the clinical features of hospitalized patients with chronic heart failure(CHF) in hospitals with different level in Xinjiang province and analyze the epidemiology of CHF including the general condition, etiology and pharmacological therapy.Methods:A cross-sectional study for hospitalized patients with CHF was applied in 20 medical centers from the year of 2012to 2013 in Xinjiang. These patients’age, gender, nationality, etiology of disease, classification of cardiac function, combined disease, current status of drug therapy were closely observed.Result:2295 among 5357 patients were Han nationality(42.8%), while 2255 were Uyghur(42.1%), and patients of other nationalities occupied 15.1%.65.3% of them were male, and the average age was 64.60±12.77 year. The main etiology of CHF are listed in turns as follows: Coronary heart disease(CHD,50.8%), Hypertension(31.8%), Dilated cardiomyopathy (7.2%), Pulmonary heart disease(3.0%), Rheumatic heart disease (2.3%).13.1% of the patients are with I of New York Heart Associtation (NYHA) function class,48.6% with II,32.4%with 111,15.9% with IV. Patients with Ⅲ,Ⅳ class of NYHA in municipal hospitals(63.6,74.1%), surpassed those in 3-A-Class hospitals(31%). The left atrial diameter(44.7±8.8mm,39.5±8.1mm) and left ventricular end-diastolic diameter (60.6±11.1mm,56.9±11.1mm) of CHF patients in county hospitals and municipal hospitals were larger than those in 3-A-Class hospitals(37.1±7.8mm,53.8±9.7mm), and the left ventricle ejection fraction(LVEF) was lower (41.9±10.5%vs42.3±13.0% vs46.5±12.8%). The drugs used for CHF were separately ACEI/ARB, β-blocker, aldosterone antagonist, diuretics, digitalis, and they occupied the percentage of 72.8%,66.8%,46.6%,45.5%,26.8%respectively. But ACEI/ARB and β-blocker were less used in county hospitals (61.4%,51.5%) and in municipal hospitals (72.3%,58.3%) when compared with 3-A-class hospitals (75.6%,74.3%), whereas the utililization of aldosterone antagonist in county hospitals(57.9%), and municipal hospitals(57.9%) surpassed the utilization in 3-A-class hospitals(30.6%).Conclusion:CHD and hypertension are the main cause of hospitalized CHF in Xinjiang. Patients condition are worse in county and municipal hospitals when compared with 3-A-class hospitals. ACEI/ARB,β-blocker are used less in county and municipal hospitals, whereas the utilization of aldosterone antagonist surpasses that in 3-A-Class hospitals.