| objective:Understanding of Urumqi Uigur and Han women with high-risk human papillomavirus (HR-HPV) infection status. To investigate the high-risk human papillomavirus (HR-HPV) correlation between load and cervical lesions.Methods:The prospective study on Xinjiang in Urumqi city in 20～59 years old women (1150 cases in each dimension, Han) survey conducted epidemiological questionnaire. The application of the second generation of hybrid capture II (HC-II) method, Thin prep cytology test (TCT) method in the screening of cervical carcinoma, the diagnosis is greater than or equal to ASC (TCT) with or without HR-HPV positive for colposcopy and cervical biopsy.Results:The 2300 subjects,385 cases with positive HPV test, the infection rate was 16.74%. The female Uygur, Han infection rates were:20.08%,13.39%, two national between HR-HPV infection rate compares difference to have statistical sense (P=0.000).2. Chronic cervicitis and negative group, low grade, high grade intraepithelial rheological and cervical cancer group HPV infection rates were 9.63%,84.52%,92.94%,100%, with statistical difference P=0.000 HR-HPV infection in cervical lesions of different grades. Wei, Han women in different cervical lesions in the group of lesions, HR-HPV positive rate was statistically difference rate. P=0.000.3. The positive rate of HR-HPV infection increased with the aggravation of cervical lesions, the HPV-DNA load is larger than 500, significantly increased the positive rate of cervical precancerous lesion (P=0.000)5 when HPV-DNA load is more than 1000, significantly increased the positive rate of cervical cancer (P=0.000). HSIL and cervical cancer was significantly increased in the HPV-DNA load> positive diagnostic rate 1 is less than 1 (P=0.000).Conclusion:Urumqi Uygur women in the infection rate of HR-HPV was higher than that of the hans. HPV-DNA load with the severity of cervical lesions and increase... |
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