Analysis The Characteristics Of Clinical And Metabolic On Phlegm Dampness And Non Phlegm Dampness Type Adolescent Polycystic Ovary Syndrome

Objection:By comparing the difference of clinical, endocrine and metabolism of glucose and lipid between the phlegm dampness type adolescent patients and the non phlegm dampness type adolescent patients with polycystic ovarian syndrome(Polycystic Ovary Syndrome, PCOS), explore the characteristics of clinical,endocrine and metabolic adolescents patients with polycystic ovary syndrome. Aiming to provide the basis for studying on etiology and early diagnosis of polycystic ovarian syndrome, to provide the clinical basis for the intervention and the treatment of adolescent PCOS in traditional Chinese medicine.Object and Method:The object of study is the 60 cases of adolescent PCOS patients who went to the First Affiliated Hospital of Heilongjiang University Of Chinese Medicine Department of gynaecology from 2013 April to 2015 February (aged 12-19 years). Recording the basic situation of the patients age, height, weight, waist circumference, hip circumference, menstruation, systemic symptoms and tongue and pulse, help patients to input the TCM Constitution questionnaire, PCOS external signs evaluation and laboratory tests. Divided the patients into phlegm group and non phlegm group according to the characteristics of TCM syndromes, using SPSS 21 statistical analysis and processing software package deal with the data using the methodof comparison of groups.Result:1.The body mass index、incidence of obesity and black spine skin in adolescent PCOS patients of phlegm dampness group are higher than those in the non phlegm dampness group;2.The mean waist to hip ratios of two groups patients are higher than 0.8, the incidence of abdominal obesity in the phlegm dampness group is 77.14%, while the incidence of abdominal obesity in the non phlegm dampness group is 64%;3.The testosterone、luteinizing hormone、sex hormone-binding globulin in adolescent PCOS patients of phlegm dampness group are lower than those in the non phlegm dampness group(P< 0.05);4.The fasting insulin and HOMA-IR of adolescent PCOS patients of phlegm dampness group are higher than those in the non phlegm dampness group (P< 0.01), while the insulin sensitivity index is lower than that of the non phlegm dampness group(P< 0.01).Conclusion:1.The abdominal obesity in the adolescent PCOS patients was multiple;2.The body mass index in adolescent PCOS patients of phlegm dampness group is larger and insulin resistance is more severe abnormal;3.The hyperandrogenemia and high luteinizing hormone are the features of adolescent PCOS patients of phlegm dampness group.