Objective:to observe and study dry wet eliminating phlegm to side treatment phlegmy wet block type polycystic ovarian syndrome of insulin resistance, and evaluate its effectiveness and safety, discussed the disease prevention and control mechanism to promote the use of clinical provides an objective basis.Method:choose the standard of Chinese and western medicine diagnosis PCOS patients taking30cases of dry wet eliminating phlegm to party, to take their own contrast method, period take therapeutic with liquid. Observed before and after treatment of traditional Chinese medicine, times the patients indication and menstrual cramps, pregnancy, and so on. Serum sex hormones measured six (T, E2, LH, FSH, PRL, SHBG), observed before and after treatment endocrine improved; Measure and calculation WHR, BMI, observe patients improve obesity; Measuring FINS, FPG, observe insulin resistance PCOS patients. Watch drug may appear during the adverse reactions and patient compliance. And all the data statistics analysis.Results:(1) TCM symptoms:after treatment, the treatment is improved significantly, the total effective rate of93.33%; Infertile patients rate40%pregnancy; The certificate of traditional Chinese medicine ratings, total score before and after treatment were significant difference (P<0.05).(2) the sex hormone level:after treatment, serum T SHBG, LH, LH/FSH the previous dropped significantly, with significant difference (P<0.01). Serum FSH, E2have increased slightly earlier, but no significant difference (P>0.05), PRL before and after treatment and also have no significant difference (P>0.05).(3) insulin resistance:the serum FINS, homa-ir the previous declined, with significant difference (P<0.01). Before and after treatment FPG no significant difference (P>0.05).(4) the hairy, acne, obesity:the patients with BMI, WHR, hairy and acne situation the previous significant relief, with significant difference (P<0.01).(5) B super:after treatment, the patient side or both sides PCO is to ease ovarian before, with significant difference (P<0.01).6side effects:30patients,2cases appear milk bilge,2cases appear abdominal distension, the incidence of side effects for13.33%.Conclusion:dry wet resolving phlegm can significantly improve phlegmy wet block type of clinical symptoms and signs PCOS patients, improve the endocrine, improve insulin resistance, reduce the incidence of PCO ovarian, safe and effective, have broad application prospects and deserves further study. |