The Summary And Innovation Of Clinical Research On Tubal Pregnancy By Professor Deng Gaopi

ObjectiveTo analyze and conclude clinical research on tubal pregnancy by tutor Professor Dao Gaopi, and then form a systematic retrospect and summary.MethodCollect 30 papers about clinical research on tubal pregnancy by tutor Professor Deng Gaopi and 15 thesis finished under the guidance of Professor Deng Gaopi through chinese database CNKI completely, and collate 3 research subjects about clinical research on tubal pregnancy by tutor Professor Deng Gaopi, so that to retrospective analysis, conclude and summarize, consequently, form a retrospective clinical review on tubal pregnancy systematically.Results1. Professor Deng Gaopi togather with his research team discovered that pelvic inflammatory diseases, tubal surgery history, cesarean section history, production history, induced abortion history and IUD were social risk factors for morbidity of tubal pregnancy; In addition, there was diversity in constituent ratio of production history, abortion history, pelvic inflammatory disease, history of pelvic surgery, history of ectopic pregnancy, and IUD in tubal pregnancy, which may led to different outcomes.2. Professor Deng Gaopi togather with his research team have found that the level of β-hCG, P and E2 is different among tubal pregnancy, threatened abortion and norml early intrauterine pregnancy, what is more, tubal pregnancy <threatened abortion<norml early intrauterine pregnancy;E2/P is different between tubal pregnancy and threatened abortion, tubal pregnancy>threatened abortion.3. Professor Deng Gaopi togather with his research team have built up a discriminant equation for pregnancy of unknown location, called Deng-Song discriminant equation, by using Bayes covariant discriminant. Self validation showed that the total rate of correct discrimination was 95.6%, and cross validation was 93.6%. At the same time, relevant application software have been developed.4. Professor Deng Gaopi togather with his research team innovative divided the TCM syndrome-types of tubal pregnancy into:non-rupture stage types of Taiyuanzuluo and Taiyuzuzhi, and rupture stage types of Qixuekuituo、 Zhengxuxueyu and Yujiechengzheng, based on which they have summarized main points for differentiating TCM syndrome-types of tubal pregnancy through clinical experience.5. By the study of literatures home and abroad, as well as clinical sudy, Professor Deng Gaopi have ameliorated the condition impact factor score model of tubal pregnancy.6. Professor Deng Gaopi togather with his research team have established and optimized the diagnosis and treatment scheme of Integrative Medicine for tubal pregnancy through 718 retrospective case study and 150 prospective case study, which have been proved has high effectiveness、stability and proportionality via upper retrospective case study and prospective case study.7. Professor Deng Gaopi togather with his research team have found that constitution of TCM in tubal pregnancy was composed primarily by yang insufficiency constitution, qi-insufficiencyconstitution and static blood constitution, and that mixed constitution was more popular by research on tubal pregnancy patients. Single constitution was superior to mixed constitution on drug effects, and the more complex of constitution, the worse effects.8. Professor Deng Gaopi togather with his research team have preliminary seek the change trend of β-hCG in medications of tubal pregnancy, via tracing changing curve of β-hCG; Meanwhile, they have explored influential factors, the logistic predictive regression equation and the predictive model of decision-making tree for medical effects of tubal pregnancy.Conclusion1. Risk of tubal pregnancy is increased on women who have production history, abortion history, pelvic inflammatory disease, history of pelvic surgery, history of ectopic pregnancy, and IUD, so that the possibility of tubal pregnancy should be attention.2. For pregnant women, if the level of β-hCG, P and E2 are much more lower, but the level of E2/P is higher than normal, the possibility of tubal pregnancy should be attention.3. For early pregnancy of unknown position, the Deng-Song discriminant equation or software can be used for preliminary screening.4. The new TCM syndrome-types of tubal pregnancy reflect the chinese medisine pathology of tubal pregnancy more well, which together with the ameliorated condition impact factor score model of tubal pregnancy constitute important parts of the the diagnosis and treatment scheme of integrative medicine for tubal pregnancy.5.The diagnosis and treatment scheme of integrative medicine for tubal pregnancy owns high effective rate and good stability, which also puts to good use of chinese medcine and forms treatment path of tubal pregnancy.6. Study of predictive method of drug effects in tubal pregnancy opens up new load, and mature model is hopeful.7. According to results of Professor Deng Gaopi and his research team, patients with bias constitution can accept herbal treatment before pregnant, so that to decrease the morbidity of tubal pregancy.