| ObjectiveAnorexia is a common disease in children during the stomach system permits a longer period of clinical anorexia, see the food is not greedy, a condition characterized by reduced food intake. Anorexia can lead to malnutrition in children, immunocompromised, repeated illness, long-term growth and development of anorexia severely affected children, nutritional status and mental development of children growing cause great harm. "Spleen " is conditioning the stomach function in children, improve appetite in children important rule is the appropriate method for modulating the physiological characteristics of organs of children and various stomach diseases syndrome characteristics and adopted children over the years many scientists to TCM " spleen not fill your op "as the guiding ideology, emphasizing Anorexia mainly to transport, including several children, including anorexia stomach sick a lot of clinical and laboratory research, but the use of the spleen Spleen Therapy Anorexia is rarely mentioned. Numerous clinical studies by early mentor, using spleen and stomach Spleen Deficiency Treatment of anorexia in children achieve good results. The topic to add the herb Yi Gong San addition and subtraction, and embody the principle of Spleen combining spleen qi deficiency before and after treatment by detecting the type of anorexia in serum hemoglobin (HGB), the total number of red blood cells (RBC), hematocrit change (HCT) and serum ferritin (SF),25-hydroxyvitamin D (25-OH-D) content, and explore Anorexia Treatment Spleen Spleen mechanism.MethodIn this study, a randomized controlled trial. The 50 cases of children met the diagnostic criteria of 1:1 were randomly divided into experimental and control groups, each group of 25 people. Experimental group were given oral Yi Gong San add herb party prescription as follows:heterophylla 10g, Poria 15g, Atractylodes 5~10Og, herb 5~10g, tangerine peel 6g, licorice 6g. The control group of oral zinc gluconate oral solution+domperidone+Brad’s yeast scattered. In addition to taking two or more during treatment protocol prescribed drugs, deactivate the other affect the results of Western medicine. All patients treated for 14 days. Were performed before treatment and after treatment seven symptom score and serum hemoglobin (HGB), the total number of red blood cells (RBC), hematocrit (HCT), serum ferritin (SF),25-hydroxyvitamin D (25-OH-D) of the detection.ResultsFang Yi Gong San add herb for the treatment of pediatric spleen qi deficiency type anorexia% total efficiency, the effect of the control group compared with Western medicine is good. Total effective rate between the two groups, the difference was statistically significant (P<0.05), comparing the advantages and disadvantages, Yi Gong San add herb square experimental group was better than the Western group. Hematology test results from analysis of two groups of children after treatment, venous blood hemoglobin (Hb), red blood cell count (RBC) no significant increase or decrease, the difference was not statistically significant (P<0.05); after treatment hematocrit product (HCT) than before treatment increased, but the HCT between the two groups, the difference was no significant correlation (P> 0.05); compared with before treatment, intravenous serum SF experimental group after treatment,25-OH-D are up high, and the difference was statistically significant (P<0.05); a comparison between the two groups after treatment, SF,25-OH-D was no significant difference (P> 0.05).Conclusion1. spleen qi deficiency with anorexia in children may lack vitamin D-related;2. Yi Gong San add herb can only improve the integration of children with syndromes, increased serum ferritin,25-hydroxy vitamin D levels, the results were statistically significant, improvement in symptom scores in the superior efficacy of zinc gluconate oral solution+domperidone+Brad’s yeast scattered. |