The Clinical Research On The Effect Of Own TCM Charge Hot Compress Navel Belly In Treatment Of Cancer-related Qi Stagnation And Abdominal Distension

ObjectiveIn this prospective controlled clinical studies, we aimed to evaluate the effect of own TCM charge hot compress navel belly application in cancer-related Qi stagnation and abdominal distension, and to evaluate its benefit to patients on its feasibility, safety. Providing basis for clinical use of own TCM charge application and its promotion in the Qi stagnation and abdominal distension.MethodsThrough this prospective randomized controlled clinical trials,60 patients who met the inclusion criteria were included. All of them were come form Check First Affiliated Hospital of Guangzhou University of TCM Oncology Department from April 2014 to March 2015. They were randomly divided by random sampling method into the treatment group (own TCM charge application group)and the control group. Both of the two groups were treated by orally and needed nutritional support and the therapy of strengthening the body resistance to eliminate pathogenic factors. Point to own TCM charge application group posted on this basis. In this group we adopted the own TCM charge (Semen Raphani,Wu Zhuyu, Mu Xiang, Fennel, Dang Gui,Hou Pu, Cang Zhu) external application of navel belly, twice a day,30 minutes,14 days for a course, the control group was not adopted the own TCM charge. Observed the clinical symptoms after treatment, quality of life, Karnofsky score, fart times, stool times, abdominal circumference, bowel movement times, satisfac tion and adverse events, and used SPSS17.0 in statistical analysis.ResultsBoth of the two groups had the ecqual baseline before treatment. They were comparable. After nutritional support therapy all indicators showed signs of improvement.1. The comparison between the own TCM charge application group and the control group:1)The own TCM charge application group had the improvement of clinical symptoms effective rate of 83.33% which was higher than the control group (53.33%), their validity had significant difference (P<0.05)2) The own TCM charge application group got improvement of some symptoms than the control group(P<0.05), where fart times, bowel movement times improved significantly(P<0.05), whiles tool times, abdominal circumference were no obvious improvement(P> 0.05).3)There were no significant difference in the change of body weight, Karnofsky score between the own TCM charge application group and the control group.4) After the treatment of the own TCM charge application group, There were no adverse events happened in the gastrointestinal tract, such as skin reactions, vital signs, blood system, liver and kidney function. Incidence of adverse events in both groups had no statistical difference (P<0.05)ConclusionOn the basis of nutrition support therapy, the using of own TCM charge application group would better ease Qi stagnation and abdominal distension, would improved the quality of life and relifed fart times, bowel movement times of patients. Throughout the course, There were no adverse events happened in the gastrointestinal tract, such as skin reactions, vital signs, blood system, liver and kidney function.The patients had good satisfaction and safety. Therefore the Own TCM charge hot compress navel belly was a safe and effective adjuvant therapy in the treatment of Cancer-related Qi stagnation and abdominal distension and was worthy of clinical promotion.