The Life Quality Influence And NPY On Tian Di Jiang Ya Granule For Treatment Patient With Essential Hypertension Of Yin Lack Yang Excessive

Objective:1.to observe the effect of the particles on the yin earth buck hypertensive patients with blood pressure levels and quality of life.2. to observe the effect of the particles on earth buck hyperactivity in hypertensive patients with NPY (neuropeptideY) levels.3. Comparison of Chinese and Western medicine treatment group and the control group only western difference before and after treatment efficacy.Methods:1. Selected cases using randomized controlled design, will meet the inclusion criteria sequentially numbered. Compliance with random data table and then randomly divided into:amlodipine-Tiande buck particle group (treatment group) and 35 cases of medicine amlodipine combination of conventional Western medicine group (control group), 35 cases. ① treatment group received+Tian Di Jiang Ya Granule a bag particles (two bags for one dose), two times a day, for 28 days. ② control group regimen:conventional medicine. 5 days after yet another standard hydrogenation hydrochlorothiazide tablets 12.5 mg/day; 5 days yet standards are appropriate to add other classes of antihypertensive drugs.Detecting blood pressure, height, weight, C-reactive protein, neuropeptide Y, lipids, detect heart, liver, renal function, blood, urine. Ambulatory blood pressure, electrocardiogram. Collected and analyzed before and after treatment quality of life scale.Results:1.After treatment with amlodipine-Tiande buck particles amlodipine combination of conventional Western medicine group and blood pressure medicine group were significantly lower than before treatment, the difference was significant (P<0.01), but the combination of amlodipine group of particles is relatively better than the Tian Di Jiang Ya Granule and amlodipine combination of conventional Western medicine group has certain advantages (P <0.05).2. After treatment with amlodipine-Tiande buck particle group and pure amlodipine medicine plasma NPY content than before treatment were significantly lower, the difference was significant (P<0.05), but the amlodipine-Tiande group buck particles relatively better than amlodipine combination of conventional Western medicine group (P<0.05).3. After treatment, symptoms and quality of life has improved, but amlodipine-Tiande Group buck particles relatively better than amlodipine combination of conventional Western medicine group, there was a significant difference (P<0.05).4. Patients in both groups had no special treatment discomfort during the treatment of liver, kidney, heart function showed no obvious abnormalities.Conclusions:1. Before and after treatment, both groups can lower blood pressure pressure, but aspects of efficacy, simple is better medicine group amlodipine Pingxi Granules group. together regulators, possibly in combination with western medicine synergies Differential Treatment and Herbal Prescription comprehensive treatment of hyperactivity hypertension related.2.Amlodipine combination reduced the average particle world antihypertensive amlodipine group and simple Western NPY water, and the amlodipine group Tiande buck particles relatively better than amlodipine therapy can reduce plasma NPY levels.3. Groups could reduce the quality of life score, but amlodipine-Tiande Group buck particles relatively better than amlodipine combination of conventional Western medicine group.4. Groups can improve TCM syndrome, but amlodipine-Tiande Group buck particles relatively better than amlodipine medicine group.5. Throughout the implementation process of the subject treated patients had no obvious discomfort, and the blood, urine, liver, kidney, no obvious abnormalities, indicating that the world buck particles no significant side effects.