| Objective: In this study, Xinle Kang in the treatment of insomnia and mildanxiety as the experimental group, for a new generation of insomnia drugseszopiclone as control group. By observing and comparing the two in improving theefficacy of insomnia and anxiety, compared with two in improving the efficacy of twoanxiety factor in state anxiety, and to explore the mechanism of Xinle Kang in thetreatment of the disease in theory,and the adverse reaction monitoring.Research methods: Observation of60cases from2013January to2013October Ping ding shan branch encephalopathy hospital outpatient, into the caseswere confirmed by PSQI scale, HAMA and TCM syndrome type in reference to the1993"Chinese medicine clinical research guiding principle" and "Chinese edition theDepartment of internal medicine" standards for the diagnosis of insomnia and mildanxiety (liver fire disturbance heart) patients. The study included60patients withinsomnia were standard with mild anxiety patients, randomly divided into two groups:Xin le Kang treatment group30cases, Es zo pi clone Tablets30cases in the controlgroup. The treatment group was given Xin le Kang, three times a day,2tablets eachtime, oral; the control group give Es zo pi clone Tablets, every day before going tobed1times, each time3mg (1tablets, oral). The4week, one course of treatment,observation of a course of treatment,4weeks.In the included trials before by PSQIscale, HAMA scale score, after2weeks of treatment and evaluation of time, againafter4weeks were compared before and after treatment, efficacy, and safety test andmonitoring and evaluation of urine routine and liver function of the two.Results: Xin le Kang group, there was significant difference between beforeand after treatment and control group in the score of PSQI scale and the components of P=0.000<0.001, the experimental group and control group were compared betweenthe groups of P=0.3140.05has no obvious difference, but in improving sleep timebetween group P=0.035<0.05had a significant difference compared, indicating thattwo groups there is no obvious difference in improving sleep, but better than thecontrol group in improving sleep time; before and after treatment, HAMA score ingroup P=0.000<0.01had highly significant difference, the experimental groupcompared with the control group showed significant differences with P=0.045<0.05,said the new Le Kang in the improvement of anxiety status was better than the controlgroup，And after treatment between the two groups of physical factor p=0.3570.005has no significant statistical significance, has the significant spiritual factorp=0.041<0.005, the curative effect of Xin le Kang on mental anxiety in the treatmentof anxiety state improved better than the control group; there was significantdifference between the experimental group and the control group in comparison withthe general effect of P=0.013<0.05, a highly significant difference in cure ratebetween the two P=0.006<0.001; no adverse reaction was in use.Conclusion: Xin le Kang in improving sleep quality on the whole group had noobvious difference with the control, but better than the control group in improvingsleep time; Xin le Kang in the improvement of anxiety status was better than thecontrol group; the overall effect is better than the Xin le Kang group, control group,cure rate compared with the control group had significant statistical significance; Inthe theory of traditional Chinese medicine center main consciousness, liver advocateemotional, Chinese medicine, there are seven emotions disease, caused by insomnia,anxiety had liver, belonging to the heart disease, but the relationship with liver is veryclose, the insomnia, anxiety disease in the heart and liver, heart treatment should bedialectical, Xinle Kang recipe of soothing the liver, is from sedative treatment.Through the observation of the liver is an important method in the treatment ofinsomnia, anxiety; adverse reaction through the experimental routine urine and liverand kidney function test both showed No. |
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