| Objective:To investigate the influence factors of Helicobacter pylori among the Armyand Navy recruits,then figure out the correlation between H.pylori,smoking,drinkingand Stress induce upper gastrointestinal disease.make sure of the effect of Blood cellsand Serum factors.1.Methods:1.A prospective survey of H.pylori infection was accomplished in a naturalpopulation of1800cases in18centers among the Inner Mongolia army and ZhouShanmarines．A questionnaire survey with62items related to H.pylori was conducted，including nation, age, degree of education,living condition before enrolling,smoking,drinking and post history of taking medication and was provided byDepartment of Epidemiology and Biostatistics, Peking University. Then,13C-urea breathtest (UBT) was used to performed so as to evaluate the present infection status．2.A prospective trial was carried out to evaluate NUD rate and its relatedfactor among the nine centers including900navies.According to the Rome Ⅲdiagnostic criteria, all subjects underwent gastroscope and laboratory check-up toexclude organic or metabolic diseases.Base on RomeⅢ classification system,data ondyspeptic syptoms were collected by using questionnaires.Potential precipitating factorsfor dyspepsia and life-style related to dyspepsia were also explored in the questionnaire.3.Statistical approach: all statistical data are processed with SPSS l7.0software, H,pylori infection rate presented in percentage, enumeration data compared with χ2-test.measurement data compared with Student’s test,the level of WBC,PG andBG Presented in±s, P <0.05for the difference was statistically significant.Multiplelinear regression models were used to analyze risk factors.Results:1.The actual number of subjects who completed questionnaires and H.pyloridetection was1655(92.0%,800Inner Mongolia army and855Zhou shanMarine),H.pylori infection rate: army:47.4%, navy:46.0%, the total infection rate was46.7%, the Inner Mongolia regional army recruits breath test positive were356caseswhile the Zhou shan subjects were393cases, There were significant inverse correlationbetween the frequency of using detergents, drinking age, eating fruits after peeling andH.pylori infection,but was closely association with the family members.There were noassociation between H.pylori infection and having pets,education level and Washinghands before meals.2.Total900soldiers were recruited from nine centers,while497soldiers weresampled, all are young male recruits,and the diagnosis of NUD was made in104people(11.56%,104/900).Prevalence was significantly higher in H.pylori infection,Alcoholdrinking,bigger family numbers.(P<0.05),There was no difference between thecomparison groups in terms of Nationality,Blood types,education level and smoking.3.There was closely correlaction between pepsinogenⅡ,PGR,Trypsinogen(AMY)and functional dyspepsia, AMY (t=2.306, P=0.022), PG Ⅱ (t=2.195, P=2.195),PGR (t=3.721, P=3.721), P <0.05(see chart8), Group serum PG Ⅱ is higher thanthe control group, AMY and PGR levels is much lower than the control group (see chart7). The other serum index difference did not reach statistical difference, P>0.05).Conclusion:There were significant inverse correlation between family numbers,thefrequency of using detergents, drinking age, eating fruits after peeling and H.pyloriinfection,If we control the risk factor,we can prevent the H.pylori infection.Theincidence rate of functional dyspepsia was11.56%, There were significant correlationbetween H.pylori infection, age, drinking,family numbers and functionaldyspepsia.Serum PGⅡis higher than the control group, AMY and PGR is much lowerthan the control group, thus we can predict the incidence rate of functional dyspepsia with serum AMY, PGⅡ, PGR. |
