The Phlegm And Dispelling Stasis Method Impact On Clinical Efficacy In Patients With MS And Insulin Resistance

Objective:Observe the phlegm and dispelling stasis method the clinical curative effect in patients with MS and insulin resistance.Methods:select60cases of MS, phlegm and blood stasis mutua,and which were randomly divided into observation group and control group30cases in each group. Both groups are accepted the standard western medicine therapy and lifestyle intervention, at the same time,the patients in observation group add of basis treatment of phlegm and dispelling stasis.All the patients were treated during the next eight weeks after a leading period of two weeks.Record respectively TCM symptom integral,basic parameters,the FPG,2hPG,glycosylated hemoglobin(HbA1c),serum insulin,blood lipid,liver and kidney function,blood routine,urine routine in the two groups before and after treatment and calculate HOMA-IR and IAI,to make a comparative analysis.Results:1. The total effective rate of patients in observation group with blood lipid and blood pressure,respectively,were93.33%,96.67%, which was better than that of control group were76.67%,80%. Comparison between both groups was statistically significant difference(P<0.05).The total effective rate of patients in observation group with blood sugar both are96.67%, comparing with90.00%and93.33%in the control group, and the difference was not significant (P>0.05).TCM symptoms markedly effective rate of the treatment group is63.33%, better than30%in the control group,the difference between the two groups was statistically significant (P<0.05).Control penetrance rate of lipid control group was53.33%, significantly better than the control group of30%, the difference between the two groups was statistically significant (P<0.05).2.After treatment,the blood pressure,WC, weight and BMI in both groups were somewhat lower through treatment.The difference was statistically significant (P<0.05).After treatment, DBP and WC were lower than the control group, the difference between the two groups was statistically significant (P<0.05), Tips drop DBP and WC aspects observation group than the control group.3.After treatment, TG, TC and LDL-C were improved in both groups (P<0.05),through the comparison between groups,the blood lipid level of observation group was lower than the control group except TQand the difference had statistical significance(P<0.05),which prompt that the observation group had better curative effect on blood lipid.4.The FPG,2hPG and FINS in both groups were significantly decreased after treatment and the difference was significant (P<0.05); After treatment, the FPG, FINS in the observation group are lower than the control group,and comparing the differences between groups was significant (P<0.05).5.After treatment,HOMA-IR and IAI in both groups were reduced, the difference was statistically significant (P<0.05); the HOMA-IR and IAI of patients in observation group were improved significantly better than those of patients in control group, while the difference was statistically significant (P <0.05).Conclusions:1.Phlegm and dispelling stasis method can be used in the treatment of MS by phlegm and blood stasis, to improve patients the TCM syndrome2.Phlegm and dispelling stasis method can obviously relieve the metabolic disorders symptoms of patients with MS,reduce blood pressure,blood glucose and blood lipid, but the individual indicators such as hip circumference,improving insulin resistance in patients with MS and increasing insulin sensitivity.3.Phlegm and blood stasis by law may improve insulin resistance, increased insulin sensitivity, play a therapeutic role in MS.