The Clinical Research On Treatment Of Cangfu Daotan Decoction And Insulin Sensitization Agent In Metabolic Syndrome

Subjective:By randomized controlled clinical research, observation pale attached guide phlegm tonga subtraction side joint insulin sensitization agent with simple insulin sensitization agent treatment the clinical curative effect of metabolic syndrome, from a patient’s recent objective biochemical indicato rs and clinical common symptom, the influence of adverse reaction, etc, comprehensive, true and obj ectively evaluate the pale attached guide phlegm tonga minus the clinical curative effect of treatment of the metabolic syndrome, provide the basis for clinical application, to further demonstrate advanta ges and characters of traditional Chinese medicine treatment of the metabolic syndrome.Methods:Using randomized controlled clinical trial method,60 cases met inclusion criteria were rand omly divided into two groups:experimental group and control group, each 30 people.Control group t ake on the basis of the healthy lifestyle of primary intervention measures and taking metformin and pioglitazone.Patients in the control group on the basis of taking pale attached guide phlegm tonga su btraction.28 days for a treatment cycle, after 3 cycles, observe and compare the curative effect of th e drug was 2 groups of patients with the metabolic syndrome.Results:The general index of the two groups of patients after treatment compared with before treatm ent, body weight, body mass index, systolic pressure, diastolic blood pressure were significantly lowe r, the difference was statistically significant (P<0.05);Treatment group after treatment waist circumf erence compared with before treatment in the group, the difference was statistically significant (P< 0.05);Experimental group waistline and systolic blood pressure after treatment compared with the con trol group after treatment, the difference was statistically significant (P<0.05).Two groups of patient s after treatment of blood glucose compared with before treatment, the levels of FBG, PG2h, HbAlc were significantly lower, the difference was statistically significant (P<0.05);The treatment group was lower FBG, PG2h, HbAlc effect is better than that of control group (P<0.05).Insulin secretion level, INS2h level decreased significantly after treatment in both groups, the difference was statistic ally significant (P<0.05), the effect of the treatment group reduced INS2h is better than that of co ntrol group (P<0.05).Comparison of two groups before and after treatment in patients with insulin resistance index compared with before this treatment levels drop, statistically significant (P<0.05);T reatment group after treatment than the control group after treatment of insulin resistance index fell more obvious, statistically significant (P<0.05).The comparison of two groups of patients before an d after treatment the blood fat compared with before this treatment, TC, LDL-C levels drop, statis tically significant (P<0.05);Treatment group after treatment than before treatment TG levels drop, st atistically significant difference (P<0.05);Group HDL-C increased after the treatment (P<0.05), the control group was not seen the obvious change (P=0.079);Treatment group after treatment com pared with control group after treatment are the obvious TC levels drop, statistically significant (P< 0.05).Treatment-related adverse reactions, patients with less adverse reaction, high security.Conclusion:Pale attached guide phlegm decoction treatment of metabolic syndrome can improve clini cal symptoms not only reduce the waist circumference, weight loss, control of blood pressure, blood glucose, blood lipid, but also can improve insulin secretion, insulin resistance.The drug safety, no o bvious adverse reaction, worthy of clinical promotion and further study.