The Clinical Research On The Combination Of Shallow Insertion And Fluoxetine Hydrochloride In Treating Depression With Liver-qi Stagnation Type

AIM:To observe the clinical effect and safety evaluation on the combination of shallow insertion and Fluoxetine hydrochloride in treating depression with Liver-qi stagnation type,and explore the shallow insertion therapeutical effect on depression. METHOD:60patients,who have depression with Liver-qi stagnation type,were randomly divided into treatment group and control group,every group has30patients.In treatment group, superficial insertion and Fluoxetine hydrochloride were used.Control group only use Fluoxetine hydrochloride.Two groups have the same dosage and administration in Fluoxetine hydrochloride application.The dosage is20mg/d,which was taken after breakfast30min,and last6weeks as one course of treatment.Refer to clinical experience of treating depression by tuter groups. We choose Shen-Ting,Bai-Hui,Nei-Guan(both sides),Tai-Chong(both sides),which are treated with reducing method,and choose Shen-Men(both sides),which are treated with reinforcing method.Every time every point have to finish two therapeutic dose,and treat3days a week(Monday,Wednesday,Friday),last6weeks.Observe:(1)We evaluat depressive patients by HAMD Scale at baseline,2,4,6weeks after the treatment;(2)According to the typing standard of affective disorder in the TCM symptom diagnostic criteria for curative effect,and quantification.We evaluat the patient at baseline,6weeks after the treatment;(3) Rating scale for side effects(SERS) is used rating Fluoxetine hydrochloride from1week after the treatment. Using statistical software SPSS18.0statistical analysis of data. RESULT:1. Two groups in the sex proportion, the age, the course of an illness length, HAMD depression scale score, TCM rating scale do not have statistics difference, do not have the significant difference(P>0.05);2. After the treatment course had ended, the treatment group (shallow insertion with Fluoxetine hydrochloride) cures19examples, shows results6examples, effective3examples, invalid2examples; control group(Fluoxetine hydrochloride) cures10examples, shows results11examples, effective5examples, invalid4examples; Two groups of clinical curative effects after statistics analysis, have the significance difference (P<0.05).3. In the treatment of the2nd, the4th, the6th weekend,HAMD scale score between the two groups quite are even have statistics significance (P<0.05);4. Two groups in TCM rating scale have significance difference at6weeks after treatment(P<0.05).5. Two groups in the treatment in Rating scale for side effects(SERS) have significance difference (P<0.05).CONCLUSION:1. The combination of shallow insertion and Fluoxetine hydrochloride for the treatment of depression has the very good clinical curative effect.2. The combination of shallow insertion and Fluoxetine hydrochloride can more quickly and comprehensively improve the patient’s depression, and less side effects, has the quick,good curative effect, security advandage,and so on.3. The shallow insertion overcoming the slow onset and much more side effects of antidepressant.It can improve the depression patient’s survival quality quickly.