Study Of Acupuncture Pretreatment Regulating Zhimu Prompting Permeating Ability Of Diabteic Retinopathy

1.Objective Through the injection union to DR the influence, discusses the injection union the mechanism, provides the experiment take the time as the clinical injection union reasonable choice to rest on.2.Method Constructs diabetes big mouse model with STZ-CFA, the observation different method of treatment to the big mouse oxidation resistance ability, the retina permeability, the blood sugar, the body weight, the blood biochemistry target influence.3.Results Take oxidation resistance target (SOD, MDA, GSH-Px), cataract formation rate, blood sugar and so on as observation target.Oxidation resistance target:(1)SOD:The tendency for (knows mother+pre-needle group> pre-needle group> to know mother+acupuncture group)> the masculine group> to know the female group> model group;(2)MDA:The tendency for (knows mother+pre-needle group> to know mother+acupuncture group, pre-needle group, knows female group)> the masculine group> model group;(3)GSH-Px:The tendency for (knows mother+pre-needle group> to know mother+acupuncture group, pre-needle group)> knows the female group, the masculine group, the model group.Cataract formation rate:The model group and the masculine group with know the female group and know the mother+pre-needle group the difference to have statistics significance (P<0.003333); Knows the female group, knows the mother+acupuncture group, knows mother+pre-needle group, the pre-needle group22between differences does not have statistics significance (P>0.003333).Blood sugar: Knows the mother+pre-needle group blood sugar change to have the remarkable change, obviously surpasses the model group, the masculine group, knows the female group, knows the mother+acupuncture group, the pre-needle group (P<0.05); Obviously is higher than the normal group, the difference has statistics significance (P<0.05).4.Conclusion(1) Doctor practicing western medicine method effect difference:The doctor practicing western medicine method of treatment regarding diabetes big mouse oxidation resistance ability, cataract formation rate, the blood sugar, the body weight, the liver function, the kidney function, the heart function, fat metabolism, the inorganic salt ion, the hemoglutination function influence effect is different, in which injection union surpasses the pure acupuncture or the pure China and the West medicine.(2) Pre-injection unions and pure acupuncture and pure Chinese native medicine effect difference: The acupuncture and the medicine are very difficult to compare which one is good and which one is bad, they display the difference to diabetes big mouse’s intervention function in the different aspect, or the acupuncture surpasses the Chinese native medicine, or the Chinese native medicine surpasses the acupuncture, but the pre-injection union is generally surpasses the pure acupuncture or the pure medicine.(3) Common injection unions and pre-pure acupuncture and pure Chinese native medicine effect difference:Knows the female group+acupuncture group has the difference with the pre-pure acupuncture and the pure Chinese native medicine to diabetes big mouse’s influence effect.In the oxidation resistance aspect, knows the female group+acupuncture group to surpass the pure acupuncture and the pure Chinese native medicine obviously; In the blood sugar control aspect, knows the female group+acupuncture group not to display the injection union actually the superiority, instead is displays the business trip in the pure acupuncture and the pure Chinese native medicine tendency, explained is not the injection union all can surpass the pure method of treatment.(4) Acupuncture intervention time effect difference:The different acupuncture intervention time regarding the big mouse oxidation resistance ability, cataract formation rate, the blood sugar, the body weight, the liver function, the kidney function, the heart function, fat metabolism, the inorganic salt ion, the hemoglutination function influence effect is different, displays for carries on the injection union intervention to have in advance to surpass must in advance the injection union intervention, but is not all displays the difference to diabetes big mouse all aspects.(5) Experiments based on the understanding which obtains to diabetes big mouse’s application injection union method research:①The acupuncture has the obvious oxidation resistance function, does not have the close relation with the intervention time;②The injection union needs to grasp the good intervention time, is generally Vietnam is early more effective;③The injection union can have the function which the pure acupuncture and the pure medicine all do not have;④The injection union overall carries on the adjustment to organism.