The Clinical Study On Xin Wei San Treating Stable Angina Pectoirs Due To Syndrome Of Qi Stagnation And Phlegm Stasis

Objective：To observe the clinical curative effect of treating syndrome of Qi-astheniaand Phlegm-Stasis of stable angina caused by coronary heart disease through applying thexin wei san and To explore its mechanism.Methods：60patients with stable angina of coronary heart disease were randomlydivided into the experimental group (30cases) and the control group (30cases). Eachgroup was treated with Western medicine as a primary treatment.The experimental groupwas dosed xin wei san. The course of clinical treatment is four weeks.Results: After4weeks treatment, angina pectoris, experimental group, markedlyeffective rate was40%, total effective rate was86.67%;control group, markedly effectiverate was20%, total effective rate was73.33%. Medicine Clinical symptoms of theexperimental group was markedly40%, total effective rate was86.67%;markedly effectiverate was20%in control group, the total effective rate was53.33%. EKG, experimentalgroup that was30%, total effective rate was76.7%;markedly effective rate was26.67%incontrol group,the total effective rate was73.33%.There were not significant differences (P＞0.05). Nitroglycerin stopped nitroglycerin stopped reduction rate, test group reductionrate is83.33%, the control of nitroglycerin stopped reduction rate is60.00%, P=0.045iscompared between groups (P <0.05)。Treatment group before and after treatmentcomparison, TC, LDL decreased obviously, there is significant difference (P <0.05), HDLsignificantly increases, there is significant difference (P <0.01), TG decreased, there wasno significant difference (P>0.05), the control group compared with TC, TG, LDL fell, butthere was no significant difference of HDL was increased, there was no significantdifference (P>0.05). Compared with the control group, experimental group after treatment,Blood Rheology were greatly improved(P<0.05). Conclusions：This study shows that heart stomach powder on stable angina pectorisclinical efficacy significantly, can significantly relieve angina symptoms, reduce thedosage of nitroglycerin, can adjust blood lipid (TC, TG, LDL, HDL), improve myocardialischemia, ease discomfort symptoms such as chest pain, chest tightness, improve theclinical curative effect, can be used for clinical purposes. Treatment in the process of twogroups of patients were no significant adverse reactions.