The Clear Circulation Hot Party Clinical Study Of The Treatment Of Type2Diabetes Stasis Heat Competing Card

Objective:To discuss the understanding of traditional Chinese medicine about type2diabetes, using Prescription of removing heat and eliminating bloodstasis.To observe the therapeutic efficacy of this method in treating the syndrome stagnated heat of type2diabetes.Methods:A randomized,controlled trial was conducted67cases with the syndrome of stagnated heat of type2diabetes. Randomly divided into treatment group (34cases) and control group (33cases). In lifestyle intervention and on the basis of conventional western medicine treatment, the treatment group adding in traditional Chinese medicine,3months was a course of treament. To observed indexes included both curative effect indexes,such as clinical symptoms. FBG,PBG,HbAlc,blood fat,hemorheology and inflammatory factor such as hs-CRP,TNF-a,IL-6,and safety indexes,such as blood and stool test,routine urine,the function of liver and kidney,and the adverse reaction and compliance of patients. All the data analysis by SPSS19.0statistical software.Results:Prior treatment, thegender, age, course of disease,BMI of the two groups patients had no differences.(1) traditional Chinese medicine syndrome:two groups before and after treatment were improved, the treatment group total effectiveness is better than the control group.(2) blood sugar:two groups of patients before and after treatment of fasting plasma glucose, postprandial2hours blood glucose, glycosylated hemoglobin were significantly decreased, there’s no significant differences between two groups.(3) blood fats:the treatment group after treatment in patients with TC, TG, LDL-C level drops, HDL-C levels rise. In control group TC, TG, LDL-C level drops, HDL-C level had no statistical difference before treatment. Comparison between groups the in treatment group’s TC, HDL-C, LDL-C level was lower than the control group’s.(4) blood rheology:the treatment group after treatment whole blood viscosity (high shear, cut and low cut5/s), plasma viscosity, blood sedimentation was decreased with significant differences. Control group in whole blood viscosity (in low cut, cut5/s) and blood sedimentation was decreased with statistically significant, the whole blood viscosity (high shear, the plasma viscosity) was no statistically difference between before and after treatment. Comparison between groups the whole blood viscosity (high shear, low cut5/s), plasma viscosity, blood sedimentation has a statistically significant difference between the falling degree, whole blood viscosity (slice) no significant differences.(5)Inflammation factor: the treatment group after treatment the hs-CRP, TNF-a, IL-6was reduced.The Control’s hs-CRP, TNF-a was no obvious difference, the IL-6was decreased. Comparison between groups the hs-CRP, TNF-a, IL-6levels lower than the control group, with statistical differences.Conclusion:From preliminary clinical studies, treatment of western medicine pooling blood heat effect is better than pure western medicine treatment, Chinese medicine treatment can improve clinical symptoms, reduce blood sugar, adjusting blood fat, also can improve the blood rheology, inflammation, and safe, effective. So it has extensive application prospect and is worth further study.