| Purpose:Trying using the research technique of the "syndrome factor dialectical method" in TCM(Traditional Chinese Medicine), investigate the distribution regularities of syndrome factor in primary dyslipidemia. While analyzing the dependency between syndrome factor and blood lipid indexes, try to explore the objective basis of the treatment based on syndrome differentiation of TCM. On the same time, in order to find more ways to strengthen the effect of treatment of TCM, we use the emotion theory of TCM to observe the distribution regular i ties of the related syndrome factor and the influence to the blood fat of the emotional factor.Methods:1. Based on the related literature summary of primary dyslipidemia and related teaching material on concept of symptom, screen out symptom of primary dyslipidemia including emotional symptoms, diagnostic dyslipidemia information as clinical questionnaire.2. Collect the data of120cases of primary dyslipidemia, including common data, Hamilton anxiety scale, Hamilton depressive scale, clinical quest ionnaire, blood lipid index (TC,TG,HDL-C, LDL-C, ApoAl, ApoB, Lp-a). Then analyze the data according to the "syndrome factor dialectical method"3. Statistics:Describe the count data using proportion or percentage, and measurement data using the mean±standard deviation. Counts are compared by chi-square test, and measuring between two groups is compared with t test. Comparisons of multiple groups of data are analysis of variance. Correlation analysis of two t factors are using by linear correlation. For the data collected by Acces2007, statistical processing are used by SPSS17.0.Results:1. The percentage of the patients who have unhealthy diet habit is80%, whose TC,TG, LDL-C levels is above the normal diet of patients. Smoking patients’ TC, LDL-C lever is higher than non-smoking patients, and HDL-C, apoAl lever is lower than non-smoking patients.2. Analys is on anxiety neuros is or depress ion distr ibut ion shows that24.11%of patients may have anxiety and depression symptom, and anxiety symptom group’ TC, LDL-C lever is higher than the normal group. While having the symptoms of depression group’LDL-C lever is higher than the normal group.3. According to the analysis of clinical symptom distribution:the maximum frequency of the symptom is irritability (66%).4. According to the analysis of the syndrome elements in the primary dyslipidemia indicate diagnosed as liver’s rate being the highest (77.5%).5. Liver syndrome is associated with TC, TG, LDL-C lever positively; Kidney is associated with HDL-C, apoAl negatively; Spleen is associate with TC, TG positively; Wet syndrome elements is correlated with TC pos i t ively; Stagnation of the circulation of vital energy is correlated with TG positively; Yang hyperactivily is correlated with TC negatively. Deficiency of yin is related to HDL-C, apoAl negat ively. I1DL-C decreased with the increase of degree; Yin deficiency, IIDL-C, apoAl decreased.Conclusions:The dysfunction of liver is the most important pathogenes is of TCM in primary dysl ipidemia, at the same time, the dysfunction of kidney is more prominent than the spleen’s. The disease characteristics show that more performance for the inclus ion of intermingled defic iency and excess. The syndrome elements of liver, kidney, spleen, both qi and Yin, Yang, wet, were correlated with the part of the lipid index. When IIDL-C, apoAl lever decreased, We diagnose the problem in kidney and yin deficiency possibility. There are some people with primary dys lipidemia have anxiety or depress ive symptoms, which should be paid at tention. In the treatment of primary hyper lipidemia, we should pay more attention to regulate the patients’ emotion. At the same time, we should nourish and sooth the liver, with regulating the flow of vital energy and remove obstruetion toit, tonifying qi and nourishing Yin,to adjust the body’s Yin, Yang and Qi, blood. |