Herbal Compound Qing Qin Liquid On Acute Gouty Kidney Damage Intervention Effect Of Clinical Research

In the acute attack of gout,by the stimulation of inflammatory factors, uric acid crystals deposite further to the renal interstitial tubular, furthermore impaireing renal tubular function because of lockage by physical action, gradually affecting the glomerular filtration rate, resulting in renal dysfunction. In the observation of numerous clinical cases of acute gout, found that part of the first episode of acute gout and acute exacerbation of recurrent gout can be seen in the performance of impaired renal function, which characteristics are: accompanied by uric acid above the normal biochemical parameters, at the same time, the reversibility of serum creatinine, blood urea nitrogen and urinary protein marker of renal function mild or moderately elevated reversed, with the remission of gout drug, in addition, after the intervention can greatly shorten the course. Prompt gout attacks can occur early kidney damage. The thesis focuses on acute gout, in order to explore the impact on renal function and the Intervention of herbal compound Qing Qin liquid, which has a great significance in the early prevention and treatment of clinical gouty kidney damage.1Literature reviewIn the literature review section, from the Chinese and Western medical point of view summarizes the progress in the research of acute gouty kidney damage, moreover the Ancient and Modern Medical various Research Progress name of disease etiology and pathogenesis, and treatment of gout and gouty kidney damage. Comprehensively summarized epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment of gout and hyperuricemia in the forefront of academic achievements Western medicine, in addition the incidence of acute gouty kidney damage factors and molecular mechanisms of the system Summary. A large number of cases of clinical observation combined with the literature review, we found a clear effect of the limitations of Western medicine treatment of the disease and Chinese medicine treatment of the disease. Supervisor Professor Meng Fengxian think that the hot and humid stasis spleen and kidney deficiency is based on years of clinical experience, the characteristics of the pathogenesis of acute gouty kidney damage, hot and humid stasis, spleen and kidney deficiency type is acute gouty kidney damage syndromes, governance Huazhuo Xiaoyu, help kidney spleen, evil security is, since the proposed the Chinese proprietary compound Youth Qin fluid treatment of the disease and achieved good effect.2Clinical studyObjective:To observe the efficacy of the compound green Qin liquid on acute gouty kidney damage, investigate the mechanism of action of Compound blue the Qin fluid diagnosis and treatment of disease, to explore the idea of treatment of traditional Chinese medicine for the treatment of acute gouty kidney damage.Methods:145cases of acute gouty kidney damage diagnostic criteria were randomly divided into treatment group and control group. Treatment group of80cases to the compound Qing Qin liquid decoction,300ml, the daily one. Bid;65cases of the control group received losartan potassium tablets oral,50mg Qd; treatment for2weeks. Before and after treatment of TCM symptom scores, changes in laboratory parameters, and statistical comparative analysis.Results:The total effective rate was92.50%, total effective rate was73.85%in the control group. Before and after treatment, there were significant differences, and the treatment group than the control group (P<0.05). Both groups significantly reduced the serum uric acid level, the groups showed no significant difference (P>0.05); improve renal function, two sets of serum creatinine, blood urea nitrogen level than before treatment were significantly improved (P<0.01), The treatment group than the control group (P<0.05); treatment and control groups could significantly reduce urinary protein in patients, and the treatment group than the control group (P<0.05). In improving the symptoms of joint pain, joint swelling, joint function, systemic symptoms, tongue, pulse, have a significant effect, there are significant differences before and after treatment, and the efficacy of the treatment group than the control group.Conclusion:Acute gout attack can lead to kidney damage; compound green Qin solution can effectively improve the symptoms and signs of acute gout; reduce serum uric acid levels, reduce proteinuria and lower serum creatinine and blood urea nitrogen levels. Description of Compound Qing Qin fluid, hot and humid stasis spleen and kidney deficiency acute gouty kidney damage in patients with good effect in the treatment of acute gouty kidney damage worth promoting.