| Lung cancer is.a malignant tumour of the highest morbidity and mortality in the world today.In recent years, the treatment of lung squamous carcinoma has been no breakthrough, and the treatment of choice is relatively limited.Objective:In view of the present related of combine TCM in the treatment of elderly advanced lung squamous carcinoma of relatively insufficient research, this study collected in recent10years Ⅲ-Ⅳ period lung squamous carcinoma cases, hope to find the advantage of combining TCM and WM treatment of elderly advanced lung squamous carcinoma and characteristic, lay a good foundation for the prevention and treatment of TCM clinical research in the future.Methods:Collecting oncology department of Guang’an Men Hospital of China Academy of Chinese Medical Science on January1,2003-December31,2012, Ⅲ-Ⅳ period lung squamous cell carcinomas patients, a total of219cases. Unified fill in a report on the cases of lung squamous carcinoma were retrospec-tively studied, observe the basic situation, the incidence, treatment and curative effect evaluation, improvement of symptoms, overall survival(OS), one year survival rate, etc. To follow-up on February1,2013,a total of125cases.Statistical analysis of the above information summary, and use of statistical tests for differences, and then draw relevant conclusions.Results:1.Basic information:①The majority patients are men, male to female ratio is8.82:1.②Midian age is68years old (39-85)③Smoking is significantly correlated with the incidence of lung squamous carcinoma, in which more than half of patients with smoking history more than40years (53.14%)④42patients have family history of malignant tumor, the family has a certain role in the pathogenesis of lung squamous cell carcinoma, but not absolutely.⑤Complications of patients accounted for76.85%of the total number of cases, reflected the characteristics of the elderly patients, the incidence of hypertension70cases (42.16%).21cases of chronic bronchitis (12.65%), tuberculosis (TB) in16cases (9.64%), etc.⑥Starting symptoms as cough, sputum cases are the most common.2.Diagnosis and treatments:①Imageological examination with Bronchoscopy play an important role to the diagnose of lung squamous cell carcinoma (51.85%)②Clinical staging, IV obviously, concentration between the ages of60-70.③Lung cancer incidence is almost the same between the left and right sides,and the majority type is center type (76.59%), the Intermediate different-iation (45.69%).④Patients with lymph node metastasis take up93.98% (203/216). Bone metastases is the most common extrapulmonary meta-stase.followed by adrenal metastases.⑤The priority of TCM syndrom is qi and Yin deficiency syndrome.Various kinds of syndromes in clinical practice are not independent.⑥Minority patients has received surgical treat-ment. most patients did not undergo surgery treatment. The lung squamous carcinoma onset conceals.3. Therapeutic evaluation:①Most lung squamous carcinoma total median survival (MST)14months.1year survival rate was55.2%(69/125),2year survival rate was29.6%(37/88), the5-year survival rate was5.6%.②Posto-perative recurrence, especially more than70years old,or Ⅲ period with Qi and Yin deficiency type,or IV period with lung-spleen Qi deficiency type is suitable for TCM treatment. IV period midterm elderly patients who had no history of surgery, ECOG score0to2points, or elderly patients who had no history of surgery are more suited to combine TCM and WM treatment.③Surgery is as predicted survival of inde-pendent risk factors. Prognosis of lung squamous carcinoma associated with surgery, early diagnosis of early treatment is the key to good prognosis.Conclusion:The intervention of TCM can give lung squamous carcinoma treatment more choices. Postoperative recurrence-especially more than70years old,or III period with qi and Yin deficiency type,or IV period with lung-spleen Qi deficiency type is suitable for TCM treatment. IV period midterm elderly patients who had no history of surgery, ECOG score0to2points, or elderly patients who had no history of surgery are more suited to combine TCM and WM treatment. Surgery is indepen-dent factor of lung squamous carcinoma and ralated to prognosis. Comprehen-sive evaluation of the clinical situation, choose the right treatment model, is the key to treat lung squamous carcinoma. |
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