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The Epidemiological Surveys Of The Middle-aged And Elderly Bone Mineral Density In Ningyang Area

Posted on:2014-02-15Degree:MasterType:Thesis
Country:ChinaCandidate:T T TaiFull Text:PDF
GTID:2234330398461023Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
[Research Background]:Osteoporosis is not only a kind of disease that can harm to the health of middle-aged and elderly seriously, but also a common disease and frequently occurring disease in elderly people especially postmenopausal women which puts a huge life and economic burden on the family and the society. With the gradually step of our country into an aged-people society, the proportion of elderly people is increasing, the prevalence rate of osteoporosis increased significantly, its incidence has become the seventh of common diseases in the world which has become one of the leading causes of senile bone pain, fracture and fracture caused disability, fracture to death, osteoporosis’s status quo and trend is not optimistic. In today’s society, there are high levels of stress and fast-pace caused by life and work for modern people, the office time is too long, they lack of physical exercise which causes osteoporosis’s incidence rate is increasing day by day, even tended to be young. Because various treatments for osteoporosis bone so far can not let them fully recovered, it is very important of early prevention and early diagnosis of osteoporosis, which will be great help for patients, patients’ families and the society. Determine whether the patient suffers from osteoporosis, one of the best detection methods is to measure bone mineral density, we can diagnose the disease is osteopenia or osteoporosis according to the reduced level of the number of measured values, and remind patients if there is a risk of fractures combining with the history of disease and associated risk factors.[Objective]:Bone mineral density measurement onNingyang county in2131people, aiming at understanding the Ningyang county senile bone mineral density levels and the prevalence rate of osteoporosis, analyzing the relevant factors which influence osteoporosis, so as to provide the scientific basis for the prevention and treatment of osteoporosis.[Method]:Doing osteoporosis research and analysis through calcaneal bone mineral density test on the Ningyang inhabitants through field measurement and the form of questionnaire, sample of2131cases, select aged40to74years old, after the exclusion of secondary osteoporosis there are1976cases with794cases for men and1182cases for women. Understand the clients’details such as gender, age, height, weight, blood pressure, history of fractures, parental history of fractures, diet habits (smoking, drinking, drinking tea, drinking coffee), whether long-term using of hormones and other drugs which affect bone metabolism, female subjects’ menstrual history situation(including whether menopause, if menopause then ask postmenopausal years). We adopt HOLOGIC Inc Company’s HOLOGIC Sshara dry type bone mineral density analyzer to determine bone density and gain T value. We do statistical analysis grouped by gender, every five years for an age group, and do statistical analysis grouped by the women whether menopause, Using SPSS18.0statistical software to analyze data.[Results]:①Sample are grouped by every five years for an age, along with the age increasing, the risk of osteoporosis and osteopenia is on the rise, people aged50to54bone mass ratio decreased obviously, compared with people aged45to49P<0.05, it has statistical significance. Compared with people aged50to54, the bone mass ratio of people aged55to59decreased obviously, P<0.05, two sets of data between a statistically significant difference. Compared with people aged55to59, the bone mass ratio of people aged60to64decreased obviously, P<0.05, two sets of data between a statistically significant difference.②Normal population proportion of women’s bone mass before the age of50are significantly higher than male with the same age, after60years of age, Normal population proportion of women’s bone mass is significantly lower than male in the same age.③The normal bone mass ratio of menstruating women group is75.65%, bone mass loss ratio is21.04%, osteoporosis ratio is3.31%, the normal bone mass ratio of menopause women group is29.12%, bone mass loss ratio is53.10%, osteoporosis ratio is17.78%. Compared to the normal bone mass ratio of menopause women group, the normal bone mass ratio of menstruating women group declines obviously. Compared to the bone mass loss ratio of menopause women group, the bone mass loss ratio of menstruating women group rises obviously. Compared to the osteoporosis ratio of menopause women group, the osteoporosis ratio of menstruating women group rises obviously. The sets of data between a statistically significant difference. We take the independent sample t-test between whether the sample is postmenopausal and t-test, compared with the menopause women and menstruating women, P<0.001, it has a significant difference.[Conclusion]:①mineral density (BMD) was negatively associated with age in total study poBone mineral density (BMD) was negatively associated with age in total study population. BMD was decreased as the age grew, and the prevalence of osteoporosis significantly rose in subjects older than50years old.②Osteoporosis and bone mass loss were more common in middle-aged and old female than male, and the downward of BMD was milder in male than in female.③Menopause play a decisive role in the BMD change in female.
Keywords/Search Tags:Bone mineral density(BMD), Osteopo rosis, Middle-aged and elderly, Epidemiology
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